Past
Segmentectomy has become a new standard of care for patients with selected peripheral-type early-stage non-small cell lung cancer (NSCLC).1 Previous study had demonstrated that video-assisted segmentectomy (VAS) as a minimally invasive approach is safe and effective for anatomic segmentectomy.2 But the deep learning curve due to the rigid chopstick-like instruments and the two-dimensional vision has hindered its application. In recent years, robot-assisted segmentectomy (RAS) has rapidly increased due to the advantages of three-dimensional vision and articulated mechanic surgical arms. However, the outcome comparison between RAS and VAS for small pulmonary nodules remains insufficient.3,4
Present
This study performed a head-to-head comparison between RAS and VAS for small pulmonary nodules in terms of short-term outcomes. Propensity score-matching (PSM) was performed to minimize selection bias between the groups. The results suggested that the patients undergoing RAS had a shorter total operative time, less blood loss, less use of strong opioids, and a shorter postoperative stay than those undergoing VAS, indicating that RAS is a safer and more effective surgical approach than VAS in segmentectomy of small pulmonary nodules.5 Based on these findings, the authors propose that RAS will be more widely used in the treatment of peripheral early-stage NSCLC as the cost becomes lower in the future.
Future
Nevertheless, the data of this study were from a single center, and the data of the patients in the VAS group were retrospectively collected. Although PSM was performed in this study, some confounding factors that might have had an impact on the outcomes still existed. Therefore, more data from other centers are needed to confirm the results.
References
Saji H, Okada M, Tsuboi M, et al. Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial. Lancet. 2022;399:1607–17.
Ghaly G, Kamel M, Nasar A, et al. Video-assisted thoracoscopic surgery is a safe and effective alternative to thoracotomy for anatomical segmentectomy in patients with clinical stage I non-small cell lung cancer. Ann Thorac Surg. 2016;101:465–72.
Zhang Y, Chen C, Hu J, et al. Early outcomes of robotic versus thoracoscopic segmentectomy for early-stage lung cancer: a multi-institutional propensity score-matched analysis. J Thorac Cardiovasc Surg. 2020;160:1363–72.
Zhou Q, Huang J, Pan F, et al. Operative outcomes and long-term survival of robotic-assisted segmentectomy for stage IA lung cancer compared with video-assisted thoracoscopic segmentectomy. Trans Lung Cancer Res. 2020;9:306–15.
Yang M, Tan Z, Li J, et al. Comparison of short-term outcomes between robot-assisted and video-assisted segmentectomy for small pulmonary nodules: a propensity score-matching study. Ann Surg Oncol. 2023. https://doi.org/10.1245/s10434-023-13179-y.
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Yang, MZ., Yang, HX. ASO Author Reflections: Which Technique is Superior for Segmentectomy of Small Pulmonary Nodules: Robot-Assisted or Video-Assisted?. Ann Surg Oncol 30, 2765–2766 (2023). https://doi.org/10.1245/s10434-023-13180-5
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DOI: https://doi.org/10.1245/s10434-023-13180-5