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Effect of Patient-Participation Continuous Nutritional Counseling in Gastric Cancer Patients who Underwent Gastrectomy

  • Gastrointestinal Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

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Abstract

Background

Body weight loss (BWL) and skeletal muscle loss (SML) are inevitable after gastrectomy for gastric cancer (GC) and can decrease patients’ quality of life (QOL) and survival.

Objective

The aim of this retrospective study was to evaluate the effect of perioperative and post-discharge patient participation in continuous nutritional counseling (CNC) on post-gastrectomy BWL and SML.

Methods

Ninety-three patients with GC who underwent curative gastrectomy between March 2018 and July 2019 were analyzed. Patients received either pre-discharge nutritional counseling alone (control group, n = 49) or patient-participation CNC (CNC group, n = 44) after gastrectomy. Differences between percentage BWL (%BWL), percentage SML (%SML), and nutrition-related blood parameters between the preoperative values and those at 12 months after surgery were compared between the groups.

Results

Compared with the control group, %BWL was significantly lower in the CNC group at 1 month (−6.2 ± 2.5% vs. −7.9 ± 3.3%, p = 0.005), 6 months (−7.8 ± 6.6% vs. −12.3 ± 6.4%, p = 0.001) and 12 months (−7.9 ± 7.6% vs. −13.2 ± 8.2%, p = 0.002), and %SML was significantly lower in the CNC group at 12 months (−5.3 ± 10.3% vs. −12.8 ± 12%, p = 0.002). Regarding nutrition-related blood parameters, change in total cholesterol was significantly lower in the CNC group than the control group at 12 months after surgery (p = 0.02). Multivariate analysis identified no CNC as an independent risk factor for severe BWL (p = 0.001) and SML (p = 0.006) at 12 months after surgery.

Conclusions

Following gastrectomy, patient-participation CNC prevented postoperative BWL and SML after surgery. These results support the induction of such a CNC program in these patients.

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Change history

  • 11 November 2022

    Affiliation number 1 was corrected.

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Acknowledgment

The authors wish to thank all patients who contributed their data for analysis in the present study.

Funding

No sources of funding were used to assist in the preparation of this study.

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Authors and Affiliations

  1. Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan

    Nobuo Takata MD, Satoru Kikuchi MD, PhD, Shinji Kuroda MD, PhD, Shunsuke Tanabe MD, PhD, Naoaki Maeda MD, PhD, Kazuhiro Noma MD, PhD, Yuzo Umeda MD, PhD & Toshiyoshi Fujiwara MD, PhD

  2. Department of Gastroenterological Surgery, Kochi Health Sciences Center, Kochi, Japan

    Nobuo Takata MD & Kazuhide Ozaki MD, PhD

  3. Department of Clinical Nutrition, Okayama University Hospital, Okayama, Japan

    Ayako Takahashi BS & Kenichi Shikata MD, PhD

  4. Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan

    Kenichi Shikata MD, PhD

Authors
  1. Nobuo Takata MD
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  2. Satoru Kikuchi MD, PhD
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Corresponding author

Correspondence to Satoru Kikuchi MD, PhD.

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Disclosure

Nobuo Takata, Satoru Kikuchi, Shinji Kuroda, Shunsuke Tanabe, Naoaki Maeda, Kazuhiro Noma, Ayako Takahashi, Yuzo Umeda, Kenichi Shikata, Kazuhide Ozaki and Toshiyoshi Fujiwara declare they have no conflicts of interest in relation to this work.

Ethical Approval

All procedures followed were in accordance with the standards of the Ethics Committee of Okayama University Hospital and with the Helsinki Declaration of 1964 and later versions.

Informed consent

Information about the aim of this retrospective study was posted on the website of the Department of Gastroenterological Surgery, Okayama University Hospital, and potential participants could decline to participate or opt out at any time.

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Takata, N., Kikuchi, S., Kuroda, S. et al. Effect of Patient-Participation Continuous Nutritional Counseling in Gastric Cancer Patients who Underwent Gastrectomy. Ann Surg Oncol 30, 1110–1118 (2023). https://doi.org/10.1245/s10434-022-12572-3

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