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Liver Transection-First Approach in Hepatopancreatoduodenectomy for Hilar Cholangiocarcinoma: A Safe and Secure Technique for the Early Assessment of Curable Resection and Vascular Reconstruction

  • Hepatobiliary Tumors
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Abstract

Background

Hepatopancreatoduodenectomy (HPD) is often indicated in the resection of cholangiocarcinoma but is associated with high mortality.1,2,3 From a risk–benefit perspective, HPD can be justified only when curative resection is achievable.4,5,6

Methods

A liver transection-first approach is a surgical technique in which liver transection precedes pancreatoduodenectomy (PD) and skeletonization of the hepatoduodenal ligament in HPD. This approach enables an early assessment of resectability and curability.

Results

A 64-year-old with jaundice had a tumor located mainly in the proximal bile duct, spreading from the confluence of hepatic ducts (dominant in the left hepatic duct) to the intrapancreatic bile duct. The right hepatic artery and portal vein existed in close proximity to the tumor. HPD (left hemi-hepatectomy and subtotal stomach-preserving PD) with vascular resection was performed. After liver transection along the Cantlie line, the right Glissonean pedicle was collectively secured inside the liver. The right hepatic artery, right portal vein, and right hepatic duct (RHD) were isolated, and the feasibility of vascular reconstruction was confirmed. After the RHD was divided and the negative margin was confirmed, we proceeded to perform PD. The portal vein was reconstructed between the right portal vein and the portal vein trunk. The right hepatic artery was anastomosed to the second jejunal artery of the jejunal loop with the right gastroepiploic artery as an interposition graft.

Conclusion

The liver transection-first technique in HPD facilitates early assessment of curability and resectability as well as a safe and secure manipulation and reconstruction of the hepatic artery and portal vein.

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References

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Authors and Affiliations

  1. Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan

    Takamichi Ishii MD, PhD, Satoru Seo MD, PhD, Takashi Ito MD, PhD, Satoshi Ogiso MD, PhD, FACS, Ken Fukumitsu MD, PhD, Toshihiko Masui MD, PhD & Kojiro Taura MD, PhD

Authors
  1. Takamichi Ishii MD, PhD
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  2. Satoru Seo MD, PhD
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  3. Takashi Ito MD, PhD
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  4. Satoshi Ogiso MD, PhD, FACS
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  5. Ken Fukumitsu MD, PhD
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  6. Toshihiko Masui MD, PhD
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  7. Kojiro Taura MD, PhD
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Corresponding authors

Correspondence to Takamichi Ishii MD, PhD or Kojiro Taura MD, PhD.

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The authors declare that they have no conflicts of interest and received no funding support for this research.

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The patient received an explanation of the procedure and provided informed consent.

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Ishii, T., Seo, S., Ito, T. et al. Liver Transection-First Approach in Hepatopancreatoduodenectomy for Hilar Cholangiocarcinoma: A Safe and Secure Technique for the Early Assessment of Curable Resection and Vascular Reconstruction. Ann Surg Oncol 28, 2988–2989 (2021). https://doi.org/10.1245/s10434-020-09303-x

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  • DOI: https://doi.org/10.1245/s10434-020-09303-x

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