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Esophagojejunal Reconstruction After Total Gastrectomy for Gastric Cancer Using a Transorally Inserted Anvil Delivery System

  • Gastrointestinal Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Introduction

Total gastrectomy (TG) is commonly performed for the treatment of patients with gastric cancer. However, reconstruction of the esophagojejunal (EJ) anastomosis can be technically demanding, with reported anastomotic leak rates in the Western world still approaching 10–15 %. We report our experience using the transoral anvil delivery system (OrVil™) for creation of the EJ anastomosis after TG.

Methods

From 2007 to 2011, 48 consecutive patients with gastric cancer underwent open (n = 31) or laparoscopic (n = 17) TG. EJ reconstruction was performed with the transoral anvil deliver system (OrVil™) in an end-to-side fashion. Demographic, clinic, and perioperative data were obtained from a prospectively maintained database.

Results

Of the 48 patients, 83 % were male. Median age at resection was 64 years. Median body mass index was 27.1 kg/m2. Seventy-nine percent (n = 38) of patients had at least one comorbidity. Fifteen patients (31 %) had at least one perioperative complication. There was one perioperative death (2 %) following a duodenal stump leak. There were four EJ leaks (8 %) and two EJ stenoses (independent of leak; 4 %). There was one EJ leak (6 %) and one EJ stenosis (6 %) following a case that was first attempted laparoscopically. There were no deaths as a consequence of an EJ leak.

Conclusions

The use of the transoral anvil delivery system during EJ reconstruction is a safe and effective option for reconstruction after open or laparoscopic TG with acceptable mortality and morbidity. The anastomotic leak rate appears to be comparable to that of other techniques.

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References

  1. Barbour AP, Rizk NP, Gonen M, et al. Lymphadenectomy for adenocarcinoma of the gastroesophageal junction (GEJ): impact of adequate staging on outcome. Ann Surg Oncol. 2007;14:306–16.

    Article  PubMed  Google Scholar 

  2. Pacelli F, Papa V, Rosa F, et al. Four hundred consecutive total gastrectomies for gastric cancer: a single-institution experience. Arch Surg. 2008;143:769–75; discussion 775.

    Article  PubMed  Google Scholar 

  3. Siewert JR, Bottcher K, Stein HJ, Roder JD. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study. Ann Surg. 1998;228:449–61.

    Article  PubMed  CAS  Google Scholar 

  4. Oh SJ, Choi WB, Song J, et al. Complications requiring reoperation after gastrectomy for gastric cancer: 17 years experience in a single institute. J Gastrointest Surg. 2009;13:239–45.

    Article  PubMed  Google Scholar 

  5. Sierzega M, Kolodziejczyk P, Kulig J. Impact of anastomotic leakage on long-term survival after total gastrectomy for carcinoma of the stomach. Br J Surg. 2010;97:1035–42.

    Article  PubMed  CAS  Google Scholar 

  6. Huscher CG, Mingoli A, Sgarzini G, et al. Totally laparoscopic total and subtotal gastrectomy with extended lymph node dissection for early and advanced gastric cancer: early and long-term results of a 100-patient series. Am J Surg. 2007;194:839–44; discussion 844.

    Article  PubMed  Google Scholar 

  7. Okabe H, Obama K, Tanaka E, et al. Intracorporeal esophagojejunal anastomosis after laparoscopic total gastrectomy for patients with gastric cancer. Surg Endosc. 2009;23:2167–71.

    Article  PubMed  Google Scholar 

  8. Ziqiang W, ZhiMin C, Jun C, et al. A modified method of laparoscopic side-to-side esophagojejunal anastomosis: report of 14 cases. Surg Endosc. 2008;22:2091–4.

    Article  PubMed  Google Scholar 

  9. Shinohara T, Kanaya S, Taniguchi K, et al. Laparoscopic total gastrectomy with D2 lymph node dissection for gastric cancer. Arch Surg. 2009;144:1138–42.

    Article  PubMed  Google Scholar 

  10. Strong VE, Song KY, Park CH, et al. Comparison of gastric cancer survival following R0 resection in the United States and Korea using an internationally validated nomogram. Ann Surg. 2010;251:640–6.

    Article  PubMed  Google Scholar 

  11. O’Riordain DS, Buckley DJ, Waldron DJ, Kirwan WO. Purse-string suture for stapled oesophagogastric anastomosis: hand-sewn versus automatic. Br J Surg. 1993;80:734–6.

    Article  PubMed  Google Scholar 

  12. Kim HH, Hyung WJ, Cho GS, et al. Morbidity and mortality of laparoscopic gastrectomy versus open gastrectomy for gastric cancer: an interim report—a phase III multicenter, prospective, randomized Trial (KLASS Trial). Ann Surg. 2010;251:417–20.

    Article  PubMed  Google Scholar 

  13. Vinuela EF, Gonen M, Brennan MF, et al. Laparoscopic versus open distal gastrectomy for gastric cancer: a meta-analysis of randomized controlled trials and high-quality nonrandomized studies. Ann Surg. 2012;255:446–56.

    Article  PubMed  Google Scholar 

  14. Wainess RM, Dimick JB, Upchurch GR Jr, et al. Epidemiology of surgically treated gastric cancer in the United States, 1988–2000. J Gastrointest Surg. 2003;7:879–83.

    PubMed  Google Scholar 

  15. Lee JH, Paik YH, Lee JS, et al. Abdominal shape of gastric cancer patients influences short-term surgical outcomes. Ann Surg Oncol. 2007;14:1288–94.

    Article  PubMed  Google Scholar 

  16. Ojima T, Iwahashi M, Nakamori M, et al. Influence of overweight on patients with gastric cancer after undergoing curative gastrectomy: an analysis of 689 consecutive cases managed by a single center. Arch Surg. 2009;144:351–8; discussion 358.

    Article  PubMed  Google Scholar 

  17. Tokunaga M, Hiki N, Fukunaga T, et al. Effect of individual fat areas on early surgical outcomes after open gastrectomy for gastric cancer. Br J Surg. 2009;96:496–500.

    Article  PubMed  CAS  Google Scholar 

  18. Kodera Y, Sasako M, Yamamoto S, et al. Identification of risk factors for the development of complications following extended and superextended lymphadenectomies for gastric cancer. Br J Surg. 2005;92:1103–9.

    Article  PubMed  CAS  Google Scholar 

  19. Ueda J, Ichimiya H, Okido M, Kato M. The impact of visceral fat accumulation on laparoscopy-assisted distal gastrectomy for early gastric cancer. J Laparoendosc Adv Surg Tech A. 2009;19:157–62.

    Article  PubMed  Google Scholar 

  20. Hiki N, Fukunaga T, Yamaguchi T, et al. Increased fat content and body shape have little effect on the accuracy of lymph node retrieval and blood loss in laparoscopic distal gastrectomy for gastric cancer. J Gastrointest Surg. 2009;13:626–33.

    Article  PubMed  Google Scholar 

  21. Makino H, Kunisaki C, Izumisawa Y, et al. Effect of obesity on laparoscopy-assisted distal gastrectomy compared with open distal gastrectomy for gastric cancer. J Surg Oncol. 2010;102:141–7.

    Article  PubMed  Google Scholar 

  22. Yasuda K, Sonoda K, Shiroshita H, et al. Laparoscopically assisted distal gastrectomy for early gastric cancer in the elderly. Br J Surg. 2004;91:1061–5.

    Article  PubMed  CAS  Google Scholar 

  23. Hwang SH, Park do J, Jee YS, et al. Risk factors for operative complications in elderly patients during laparoscopy-assisted gastrectomy. J Am Coll Surg. 2009;208:186–92.

    Google Scholar 

  24. Lee HJ, Kim HH, Kim MC, et al. The impact of a high body mass index on laparoscopy assisted gastrectomy for gastric cancer. Surg Endosc. 2009;23:2473–9.

    Article  PubMed  Google Scholar 

  25. Smith DL, Elting LS, Learn PA, et al. Factors influencing the volume-outcome relationship in gastrectomies: a population-based study. Ann Surg Oncol. 2007;14:1846–52.

    Article  PubMed  Google Scholar 

  26. Kunisaki C, Makino H, Takagawa R, et al. Efficacy of laparoscopy-assisted distal gastrectomy for gastric cancer in the elderly. Surg Endosc. 2009;23:377–83.

    Article  PubMed  Google Scholar 

  27. Isozaki H, Okajima K, Ichinona T, et al. Risk factors of esophagojejunal anastomotic leakage after total gastrectomy for gastric cancer. Hepatogastroenterology. 1997;44:1509–12.

    PubMed  CAS  Google Scholar 

  28. Pol B, LeTreut YP, Hardwigsen J, et al. Mechanically stapled esophagojejunostomy. Results of a prospective series of 176 cases. Hepatogastroenterology. 1997;44:458–66.

    PubMed  CAS  Google Scholar 

  29. Takeyoshi I, Ohwada S, Ogawa T, et al. Esophageal anastomosis following gastrectomy for gastric cancer: comparison of hand-sewn and stapling technique. Hepatogastroenterology. 2000;47:1026–9.

    PubMed  CAS  Google Scholar 

  30. Doglietto GB, Papa V, Tortorelli AP, et al. Nasojejunal tube placement after total gastrectomy: a multicenter prospective randomized trial. Arch Surg. 2004;139:1309–13; discussion 1313.

    Article  PubMed  Google Scholar 

  31. Lamb PJ, Griffin SM, Chandrashekar MV, et al. Prospective study of routine contrast radiology after total gastrectomy. Br J Surg. 2004;91:1015–9.

    Article  PubMed  CAS  Google Scholar 

  32. Pesko P, Bjelovic M, Stojakov D, Sabljak P. Modified stapling technique of esophagojejunal anastomosis. Dis Esophagus. 2002;15:303–4.

    Article  PubMed  CAS  Google Scholar 

  33. Sakuramoto S, Kikuchi S, Futawatari N, et al. Technique of esophagojejunostomy using transoral placement of the pretilted anvil head after laparoscopic gastrectomy for gastric cancer. Surgery. 2010;147:742–7.

    Article  PubMed  Google Scholar 

  34. Habu H, Kando F, Saito N, et al. Experience with EEA stapler for esophagojejunostomy. Int Surg. 1989;74:73–6.

    PubMed  CAS  Google Scholar 

  35. Seufert RM, Schmidt-Matthiessen A, Beyer A. Total gastrectomy and oesophagojejunostomy: a prospective randomized trial of hand-sutured versus mechanical stapled anastomoses. Br J Surg. 1990;77:50–2.

    Article  PubMed  CAS  Google Scholar 

  36. Fujimoto S, Takahashi M, Endoh F, et al. Stapled or manual suturing in esophagojejunostomy after total gastrectomy: a comparison of outcome in 379 patients. Am J Surg. 1991;162:256–9.

    Article  PubMed  CAS  Google Scholar 

  37. Nomura S, Sasako M, Katai H, et al. Decreasing complication rates with stapled esophagojejunostomy following a learning curve. Gastric Cancer. 2000;3:97–101.

    Article  PubMed  Google Scholar 

  38. Hyodo M, Hosoya Y, Hirashima Y, et al. Minimum leakage rate (0.5 %) of stapled esophagojejunostomy with sacrifice of a small part of the jejunum after total gastrectomy in 390 consecutive patients. Dig Surg. 2007;24:169–72.

    Article  PubMed  CAS  Google Scholar 

  39. Bracale U, Marzano E, Nastro P, et al. Side-to-side esophagojejunostomy during totally laparoscopic total gastrectomy for malignant disease: a multicenter study. Surg Endosc. 2010;24:2475–9.

    Article  PubMed  Google Scholar 

  40. Inaba K, Satoh S, Ishida Y, et al. Overlap method: novel intracorporeal esophagojejunostomy after laparoscopic total gastrectomy. J Am Coll Surg. 2010;211:e25–9.

    Article  PubMed  Google Scholar 

  41. Tsujimoto H, Uyama I, Yaguchi Y et al. Outcome of overlap anastomosis using a linear stapler after laparoscopic total and proximal gastrectomy. Langenbecks Arch Surg. 2012;397:833–40.

    Article  PubMed  Google Scholar 

  42. Carboni F, Lepiane P, Santoro R, et al. Laparoscopic surgery for gastric cancer: preliminary experience. Gastric Cancer. 2005;8:75–7.

    Article  PubMed  Google Scholar 

  43. Dulucq JL, Wintringer P, Perissat J, et al. Completely laparoscopic total and partial gastrectomy for benign and malignant diseases: a single institute’s prospective analysis. J Am Coll Surg. 2005;200:191–7.

    Article  PubMed  Google Scholar 

  44. Ibanez Aguirre FJ, Azagra JS, Erro Azcarate ML, et al. Laparoscopic gastrectomy for gastric adenocarcinoma. Long-term results. Rev Esp Enferm Dig. 2006;98:491–500.

    PubMed  CAS  Google Scholar 

  45. Kim SG, Lee YJ, Ha WS, et al. LATG with extracorporeal esophagojejunostomy: is this minimal invasive surgery for gastric cancer? J Laparoendosc Adv Surg Tech A. 2008;18:572–8.

    Article  PubMed  Google Scholar 

  46. Mochiki E, Toyomasu Y, Ogata K, et al. Laparoscopically assisted total gastrectomy with lymph node dissection for upper and middle gastric cancer. Surg Endosc. 2008;22:1997–2002.

    Article  PubMed  Google Scholar 

  47. Topal B, Leys E, Ectors N, et al. Determinants of complications and adequacy of surgical resection in laparoscopic versus open total gastrectomy for adenocarcinoma. Surg Endosc. 2008;22:980–4.

    Article  PubMed  CAS  Google Scholar 

  48. Usui S, Nagai K, Hiranuma S, et al. Laparoscopy-assisted esophagoenteral anastomosis using endoscopic purse-string suture instrument “Endo-PSI (II)” and circular stapler. Gastric Cancer. 2008;11:233–7.

    Article  PubMed  Google Scholar 

  49. Allieta R, Nardi M Jr, Brachet-Contul R, et al. Laparoscopic gastrectomy for treatment of advanced gastric cancer: preliminary experience on 38 cases. Minerva Chir. 2009;64:445–56.

    PubMed  CAS  Google Scholar 

  50. Jeong GA, Cho GS, Kim HH, et al. Laparoscopy-assisted total gastrectomy for gastric cancer: a multicenter retrospective analysis. Surgery. 2009;146:469–74.

    Article  PubMed  Google Scholar 

  51. Lee SE, Ryu KW, Nam BH, et al. Technical feasibility and safety of laparoscopy-assisted total gastrectomy in gastric cancer: a comparative study with laparoscopy-assisted distal gastrectomy. J Surg Oncol. 2009;100:392–5.

    Article  PubMed  Google Scholar 

  52. Kinoshita T, Oshiro T, Ito K, et al. Intracorporeal circular-stapled esophagojejunostomy using hand-sewn purse-string suture after laparoscopic total gastrectomy. Surg Endosc. 2010;24:2908–12.

    Article  PubMed  Google Scholar 

  53. Jeong O, Park YK. Intracorporeal circular stapling esophagojejunostomy using the transorally inserted anvil (OrVil) after laparoscopic total gastrectomy. Surg Endosc. 2009;23:2624–30.

    Article  PubMed  Google Scholar 

  54. Kachikwu EL, Trisal V, Kim J, et al. Minimally invasive total gastrectomy for gastric cancer: A pilot series. J Gastrointest Surg. 2011;15:81–6.

    Article  PubMed  Google Scholar 

  55. Kunisaki C, Makino H, Oshima T, et al. Application of the transorally inserted anvil (OrVil) after laparoscopy-assisted total gastrectomy. Surg Endosc. 2011;25:1300–5.

    Article  PubMed  Google Scholar 

  56. Marangogi G, Villa F, Shamil E. et al. OrVil™-assisted anastomosis in laparoscopic upper gastrointestinal surgery: friend of the laparoscopic surgeon. Surg Endosc. 2012;26:811–7.

    Article  Google Scholar 

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Correspondence to V. E. Strong MD.

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J. LaFemina and E. F. Viñuela are co-first authors.

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LaFemina, J., Viñuela, E.F., Schattner, M.A. et al. Esophagojejunal Reconstruction After Total Gastrectomy for Gastric Cancer Using a Transorally Inserted Anvil Delivery System. Ann Surg Oncol 20, 2975–2983 (2013). https://doi.org/10.1245/s10434-013-2978-6

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  • DOI: https://doi.org/10.1245/s10434-013-2978-6

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