Correction: J Exp Clin Cancer Res 42, 9 (2023)
https://doi.org/10.1186/s13046-022-02586-w
Following publication of the original article [1], an error was identified in Fig. 4, specifically:
-
Figure 4D - AGS/CTR and AGS/KO+MDM2 have been uploaded repeatedly
Correct figure is presented below:
MDM2 is a major contributor to the function of NAT10 in gastric carcinogenesis. A Overexpression of MDM2 inhibited the upregulation of p53 and p21 proteins in NAT10-knockout AGS cells, while knockdown of MDM2 efectively reversed the inhibitory efect of NAT10 overexpression on p53 and p21. B MDM2 overexpression reversed the upregulation of p53 and p21 proteins by NAT10 knockdown in BGC823 cells. C and D The efects of NAT10 depletion on cell proliferation (C) and colonic growth (D) were rescued by transfection with MDM2, whereas cell proliferation and colonic growth of NAT10-overexpressing cells were prevented by knockdown of MDM2. E and F Cell cycle (E) and apoptosis (F) were measured in the indicated cells by fow cytometry. G MDM2 and NAT10 proteins were evaluated in NAT10-knockout AGS cells stably expressing MDM2 or vector control. H MDM2 overexpression rescued the impaired capacity of tumor growth triggered by NAT10 knockout (n=5 mice/group). Error bars, SD. *P<0.05, **P<0.01, ***P<0.001 using a two-tailed t-test
Reference
Deng M, Zhang L, Zheng W, et al. Helicobacter pylori-induced NAT10 stabilizes MDM2 mRNA via RNA acetylation to facilitate gastric cancer progression. J Exp Clin Cancer Res. 2023;42:9. https://doi.org/10.1186/s13046-022-02586-w.
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
Deng, M., Zhang, L., Zheng, W. et al. Correction: Helicobacter pylori-induced NAT10 stabilizes MDM2 mRNA via RNA acetylation to facilitate gastric cancer progression. J Exp Clin Cancer Res 42, 98 (2023). https://doi.org/10.1186/s13046-023-02676-3
Published:
DOI: https://doi.org/10.1186/s13046-023-02676-3