Correction: BMC Plant Biol 37, 207 (2018)
https://doi.org/10.1186/s13046-018-0878-0
Following publication of the original article [1], the author identified an error in the images of Fig. 2 and Fig. 3, specifically:
Furthermore, under Real-time PCR assay (RT-PCR) of Methods section Table 1 citation has to be replaced with Supplementary Table 1. The correct sentence should read as:
‘The sequences of the primers used for the RT-PCR are listed in Supplementary Table 1.’
AS-IV inhibited macrophage M2 polarization. Macrophages derived from THP-1 cells were stimulated with IL-4/IL-13 with or without AS-IV (80 μM) for 48 h. a Flow cytometry was used to quantify the expression of CD206, an M2 macrophage marker, and CD86, an M1 marker. b QT-PCR was performed to detect gene levels in M2 and M1 macrophages. M2-associated genes included PPARγ, Arg-1, and CD206, and M1-associated genes included iNOS, TNF-α, and COX2. c Representative images of M0 and M2 macrophages with and without AS-IV stained with antibodies against Arg-1 (green) and with DAPI (blue). d The levels of IL-10 and TGF-β in the cell culture supernatants were measured by ELISA. Data are presented as the mean ± SEM from three independent experiments. Compared to M0, **p < 0.01, *p < 0.05, and n.s., no significance; compared to M2, ##p < 0.01, #p < 0.05, and n.s., no significance
AS-IV inhibited the migration and invasion of tumor cells. Macrophages derived from THP-1 were stimulated with IL-4/IL-13 with or without AS-IV (80 μM) for 48 h, and the conditioned medium (CM) was collected. A549 and H1299 cells were cultured with different CM. a and b The effect of AS-IV on A549 and H1299 invasion and migration was evaluated by wound scratch assay and trans-well assay, respectively. c and d The mRNA levels of genes associated with migration and angiogenesis in macrophages. Data are presented as the mean ± SEM from three independent experiments. Compared to M0, **p < 0.01, *p < 0.05, and n.s., no significance; compared to M2, ##p < 0.01, #p < 0.05, and n.s., no significance
Reference
Xu F, Cui WQ, Wei Y, et al. Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling. J Exp Clin Cancer Res. 2018;37:207. https://doi.org/10.1186/s13046-018-0878-0.
Author information
Authors and Affiliations
Corresponding authors
Supplementary Information
Additional file 1: Supplementary Table 1.
Sequences of the primers used for PCR.
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
Xu, F., Cui, WQ., Wei, Y. et al. Correction: Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling. J Exp Clin Cancer Res 42, 70 (2023). https://doi.org/10.1186/s13046-023-02643-y
Published:
DOI: https://doi.org/10.1186/s13046-023-02643-y