Correction to: Linc-SCRG1 accelerates progression of hepatocellular carcinoma as a ceRNA of miR26a to derepress SKP2

Correction to: J Exp Clin Cancer Res 40, 26 (2021)

https://doi.org/10.1186/s13046-020-01825-2

Following publication of the original article [1], the authors identified minor errors in image-typesetting in Fig. 2, Fig. 4 and Fig. 6; specifically:

• Figure 2E: the western blot figure of GAPDH of SNU-387 (row 4) was incorrectly used; the correct image has now been used

• Figure 2E: the label of groups of western blot was incorrect; the correct label has now been used

• Figure 4B: during the production process, image distortion was introduced in the colony study of Hep3B cells; this has been corrected using the originally provided image files

• Figure 4E: the western blot figure of E-cadherin of SNU-387 was incorrectly used; the correct image has now been used

• Figure 4E: the label of groups of western blot was incorrect; the correct label has now been used

• Figure 6B: during the production process, image distortion was introduced in the colony study of Hep3B cells; this has been corrected using the originally provided image files

• Figure 6D: the transwell figures of sh-lincSCRG1 + ov-SKP2 (row 3) and sh-lincSCRG1 + in-miR26a (row 4) groups of SNU-387 and Hep3B were incorrectly used; the correct images have now been used

Fig. 2

Overexpression of lincSCRG1 dramatically promoted HCC cell proliferation and migration in vitro. Sh-lincSCRG1, sh-NC (in SNU-387 cells), ov-lincSCRG1 and ov-vector (in Hep3B cells) cell lines were established. a Cell viability was examined by MTT assays. b Oncogenic survival was assessed by colony formation assays. c Cell cycle proliferation was evaluated by flow cytometry. d Migration was determined by transwell assays. e Cell cycle-related proteins (CKD4/6 and cyclinD1) and EMT-related proteins (MMP-2/3/9, E-cadherin, N-cadherin and Vimentin) were examined by western blot analysis. In (a-e), */**/***indicates vs. The ov-vector/sh-NC group (*, p < 0.05, **, p < 0.01, ***, p < 0.001)

Fig. 4

MiR26a is negatively correlated with the proliferation and migration of HCC in vitro. Mi-miR26a, mi-NC (in SNU-387 cells), in-miR26a and in-NC (in Hep3B cells) cell lines were established. a Cell viability was examined by MTT assays. b Oncogenic survival was assessed by colony formation assays. c Cell cycle proliferation was evaluated by flow cytometry. d Migration was determined by transwell assays. e Cell cycle-related proteins (CKD4/6 and cyclinD1) and EMT-related proteins (MMP-2/3/9, E-cadherin, N-cadherin and Vimentin) were examined by western blot analysis. In (a-e), */**/***indicates vs. The mi-NC/in-NC group (*, p < 0.05, **, p < 0.01, ***, p < 0.001)

Fig. 6

LincSCRG1 promotes cell proliferation and migration of HCC via regulating the miR26a/SKP2 axis in vitro. Sh-NC, sh-lincSCRG1, sh-lincSCRG1 + ov-SKP2 and sh-lincSCRG1 + in-miR26a groups were established in SNU-387 and Hep-3B cell lines. a Cell viability was examined by MTT assays. b Oncogenic survival was assessed by colony formation assays. c Cell cycle proliferation was evaluated by flow cytometry. d Migration was determined by transwell assays. e Cell cycle-related proteins (CKD4/6 and cyclinD1) and EMT-related proteins (MMP-2/3/9, E-cadherin, N-cadherin and Vimentin) were examined by western blot analysis. In (a - d) ^*/#/&indicatesthe sh-lincSCRG1 vs. sh-NC group, the sh-lincSCRG1 + ov-SKP2 vs. sh-lincSCRG1 -group, and the sh-lincSCRG1 + in-miR26a vs. sh-lincSCRG1 group, respectively (n = 6). ^{* /#/&}, p < 0.05, ^**/##/&&, p < 0.01, ^***/###/&&&, p < 0.001

The corrected figures are given below. The corrections do not have any effect on the results or conclusions of the paper. The original article has been corrected.