Correction: Mol Cancer 13, 8 (2014)
https://doi.org/10.1186/1476-4598-13-8
Following publication of the original article [1], an error was identified in the images presented in Fig. 4, specifically:
MiR-34a functioned as a tumor suppressor in MIBC cells. A The effect of ectopic miR-34a expression on MIBC cell proliferation was investigated by CCK-8. The miR-34a activity was mediated by transfection with miR-34a mimics or inhibitor respectively. Data are plotted as the mean ± SEM of 3 independent experiments relative to mock treatments. The effect of ectopic miR-34a expression on MIBC cell tumorgenesis was investigated by B) colony-formation and C) sphere-formation assay. Quantitative analyses of D) colony and E) sphere numbers (mean + SEM; n = 3; *p < 0.05). F Relative miR-34a expression in xenografts; G) Photographs of tumors excised 38 days after inoculation of stably transfected cells into nude mice; Mean xenograft tumor volume H) and weight I) in nude mice groups after indicated treatment (mean + SEM; n = 3; *p < 0.05)
Figure 4B: incorrect images were originally used for Lenti-NC in 5637 cell line; the correct images are now used
Furthermore, two of the primer sequences listed in the Table S1 (part of ‘Additional file 3: Supplementary materials and methods’) contained typographical errors. The sequences for HGF F and GAPDH F have been corrected in the new version of the file.
The authors provided the journal with the original data files. The corrected version of Fig. 4 is provided here. The correction does not have any effect on the results or conclusions of the paper.
Reference
Li H, Yu G, Shi R, et al. Cisplatin-induced epigenetic activation of miR-34a sensitizes bladder cancer cells to chemotherapy. Mol Cancer. 2014;13:8. https://doi.org/10.1186/1476-4598-13-8.
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Additional file 3: Table S1
. Primer sets sequences used for qPCR in this study. Figure S1. CpG sites in the promoter region of miR-34a (n=14), and sequences of the primers used for amplification of converted DNA for sequenom massarray analysis. Figure S2. Expression of some well-known targets of miR-34a in 5637, T24 and HT-1376 cells following cisplatin treatment. mRNA expression of indicated genes were detected by qPCR.
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Li, H., Yu, G., Shi, R. et al. Correction: Cisplatin-induced epigenetic activation of miR-34a sensitizes bladder cancer cells to chemotherapy. Mol Cancer 21, 155 (2022). https://doi.org/10.1186/s12943-022-01614-9
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DOI: https://doi.org/10.1186/s12943-022-01614-9