Erratum to: FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development

Correction

Following publication of our recent article [1], it was brought to our attention that there are errors in Figure 5b and Supplementary Table 2.

The corrected Figure and table are given here as Figure 1 (a corrected version of Figure 5b [1]) and Table 1 (a corrected version of Supplementary Table 2 [1]).

Figure 1

Adoptive cell transfer of FoxP3- and Bcl-xL-transduced regulatory T cells suppresses collagen-induced arthritis (CIA).

Table 1 Summary of the mouse arthritis scores of the three experiments

Naive CD4⁺ T cells from DBA/1J mice were stimulated with anti-CD3 plus anti-CD28 antibodies. On days 2 and 3, the cells were transduced with retroviral constructs: vector (Mig), FoxP3 (Mig-FoxP3), or FoxP3 with Bcl-xL (Mig-Bcl-xL-2A-FoxP3). On day 6, green fl uorescent protein-positive (GFP⁺) T cells were sorted and prepared for adoptive cell transfer. CIA was induced in male DBA/1J mice (>4 months old) by one (day 0) intradermal immunization in the base of the tail with 100 μg of bovine type II collagen in complete Freund's adjuvant, containing 5 mg/mL killed Mycobacterium tuberculosis (H37Ra). On day 15 after the immunization, the mice received transduced GFP⁺ cells (2.5 × 10⁶ per mouse, six mice per group). In the following days, the arthritis clinical score was evaluated by examining the paws and using a 4-point scale: 0, normal paw; 1, minimal swelling or redness; 2, redness and swelling involving the entire forepaw; 3, redness and swelling involving the entire limp; 4, joint deformity or ankylosis or both. Values are the mean ± standard error of the mean of data obtained in three experiments, and in each experiment, six mice per group were used.