Background
Septo-optic dysplasia (SOD) is a heterogeneous malformation condition consisting of optic nerve hypoplasia, various types of forebrain defects and hormonal deficiencies. This study aims to expand knowledge about endocrine abnormalities in patients with SOD in ASEAN countries.
Material and method
Forty-eight patients (27 male, 21 female) who has been diagnosed as having SOD in ASEAN countries were clinically reviewed from medical records.
Results
Clinical manifestations and endocrine abnormalities of the patients are shown in Table 1
Conclusion
This multicenter and multinational study shows that about 20-35 % of SOD patients have endocrine abnormalities. Hypothyroidism and GH insufficiency are the most common endocrine problems associated with this condition.
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Wacharasindhu, S., Yottasan, P., Jaruratanasirikul, S. et al. A multicenter study of endocrine abnormalities in septo-optic dysplasia (SOD) in Asean countries. Int J Pediatr Endocrinol 2015 (Suppl 1), P85 (2015). https://doi.org/10.1186/1687-9856-2015-S1-P85
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DOI: https://doi.org/10.1186/1687-9856-2015-S1-P85