Schuster DP: Obesity and the development of type 2 diabetes: the effects of fatty tissue inflammation. Diabetes Metab Syndr Obes. 2010, 16: 253-262.
Article
Google Scholar
Lefterova MI, Lazar MA: New developments in adipogenesis. Trends Endocrinol Metab. 2009, 20: 107-114. 10.1016/j.tem.2008.11.005.
CAS
Article
PubMed
Google Scholar
Otto TC, Lane MD: Adipose development: from stem cell to adipocyte. Crit Rev Biochem Mol Biol. 2005, 40: 229-242. 10.1080/10409230591008189.
CAS
Article
PubMed
Google Scholar
Cristancho AG, Lazar MA: Forming functional fat: a growing understanding of adipocyte differentiation. Nat Rev Mol Cell Biol. 2011, 12: 722-734. 10.1038/nrm3198.
CAS
Article
PubMed
Google Scholar
Green H, Kehinde O: Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell. 1976, 7: 105-113. 10.1016/0092-8674(76)90260-9.
CAS
Article
PubMed
Google Scholar
Farmer SR: Regulation of PPARγ activity during adipogenesis. Int J Obes. 2005, 29: 13-16.
Article
Google Scholar
Farmer SR: Transcriptional control of adipocyte formation. Cell Metab. 2006, 4: 263-273. 10.1016/j.cmet.2006.07.001.
CAS
Article
PubMed
PubMed Central
Google Scholar
Tang QQ, Otto TC, Lane MD: Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc Natl Acad Sci USA. 2003, 7: 44-49.
Article
Google Scholar
Gregoire FM, Smas CM, Sul HS: Understanding adipocyte differentiation. Physiol Rev. 1998, 78: 783-809.
CAS
PubMed
Google Scholar
Baudry A, Yang ZZ, Hemmings BA: PKBα is required for adipose differentiation of mouse embryonic fibroblasts. J Cell Sci. 2006, 119: 889-897. 10.1242/jcs.02792.
CAS
Article
PubMed
Google Scholar
Zhang HH, Huang J, Düvel K, Boback B, Wu S, Squillace RM, Wu CL, Manning BD: Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway. PLoS One. 2009, 4: e6189-10.1371/journal.pone.0006189.
Article
PubMed
PubMed Central
Google Scholar
Xu J, Liao K: Protein kinase B/Akt 1 plays a pivotal role in insulin-like growth factor-1 receptor signaling induced 3T3-L1 adipocyte differentiation. J Biol Chem. 2004, 279: 35914-35922. 10.1074/jbc.M402297200.
CAS
Article
PubMed
Google Scholar
Green CJ, Göransson O, Kular GS, Leslie NR, Gray A, Alessi DR, Sakamoto K, Hundal HS: Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system a amino acid uptake. J Biol Chem. 2008, 283: 27653-27667. 10.1074/jbc.M802623200.
CAS
Article
PubMed
Google Scholar
Summers SA, Kao AW, Kohn AD, Backus GS, Roth RA, Pessin JE, Birnbaum MJ: The role of glycogen synthase kinase 3β in insulin-stimulated glucose metabolism. J Biol Chem. 1999, 274: 17934-17940. 10.1074/jbc.274.25.17934.
CAS
Article
PubMed
Google Scholar
Grimes CA, Jope RS: The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol. 2001, 65: 391-426. 10.1016/S0301-0082(01)00011-9.
CAS
Article
PubMed
Google Scholar
Ross SE, Erickson RL, Hemati N, MacDougald OA: Glycogen synthase kinase 3 is an insulin-regulated C/EBPα kinase. Mol Cell Biol. 1999, 19: 8433-8441.
CAS
Article
PubMed
PubMed Central
Google Scholar
Kang SR, Han DY, Park KI, Park HS, Cho YB, Lee HJ, Lee WS, Ryu CH, Ha YL, Lee DH, Kim JA, Kim GS: Suppressive effect on lipopolysaccharide-induced proinflammatory mediators by Citrus aurantium L. in macrophage RAW 264.7 Cells via NF-κB signal pathway. Evid Based Complement Alternat Med. 2011, 2011: 1-12.
Google Scholar
Jung KH, Ha E, Kim MJ, Won HJ, Zheng LT, Kim HK, Hong SJ, Chung JH, Yim SV: Suppressive effects of nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) expression by Citrus reticulata extract in RAW 264.7 macrophage cells. Food Chem Toxicol. 2007, 45: 1545-1550. 10.1016/j.fct.2007.02.017.
CAS
Article
PubMed
Google Scholar
Liu L, Shan S, Zhang K, Ning ZQ, Lu XP, Cheng YY: Naringenin and hesperetin, two flavonoids derived from Citrus aurantium up-regulate transcription of adiponectin. Phytother Res. 2008, 22: 1400-1403. 10.1002/ptr.2504.
CAS
Article
PubMed
Google Scholar
Mercader J, Wanecq E, Chen J, Carpéné C: Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium. J Physiol Biochem. 2011, 67 (3): 443-452. 10.1007/s13105-011-0078-2.
CAS
Article
PubMed
Google Scholar
Haaz S, Fontaine KR, Cutter G, Limdi N, Perumean-Chaney S, Allison DB: Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. Obes Rev. 2006, 7: 79-88. 10.1111/j.1467-789X.2006.00195.x.
CAS
Article
PubMed
Google Scholar
Jeong WY, Jin JS, Cho YA, Lee JH, Park S, Jeong SW, Kim YH, Lim CS, El-Aty AM, Kim GS, Lee SJ, Shim JH, Shin SC: Determination of polyphenols in three Capsicum annuum L. (bell pepper) varieties using high-performance liquid chromatography-tandem mass spectrometry: Their contribution to overall antioxidant and anticancer activity. J Sep Sci. 2011, 34: 2967-2974. 10.1002/jssc.201100524.
CAS
Article
PubMed
Google Scholar
Lee DH, Park KI, Park HS, Kang SR, Nagappan A, Kim JA, Kim EH, Lee WS, Hah YS, Chung HJ, An SJ, Kim GS: Flavonoids isolated from Korea Citrus aurantium L. induces G2/M phase arrest and apoptosis in human gastric cancer AGS cells. Evid Based Complement Altern Med. 2012, 2012: 1-11.
Google Scholar
Fève B: Adipogenesis: cellular and molecular aspects. Clin Endocrinol Metab. 2005, 19: 483-499.
Google Scholar
Akune T, Ohba S, Kamekura S, Yamaguchi M, Chung UI, Kubota N, Terauchi Y, Harada Y, Azuma Y, Nakamura K, Kadowaki T, Kawaguchi H: PPARγ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J Clin Invest. 2004, 113: 846-855.
CAS
Article
PubMed
PubMed Central
Google Scholar
Sun L, Nicholson AC, Hajjar DP, Gotto AM, Han J: Adipogenic differentiating agents regulate expression of fatty acid binding protein and CD36 in the J744 macrophage cell line. Lipid Res. 2003, 44: 1877-1886. 10.1194/jlr.M300084-JLR200.
CAS
Article
Google Scholar
Claycombe KJ, Jones BH, Standridge MK, Guo Y, Chun JT, Taylor JW, Moustaïd-Moussa N: Insulin increases fatty acid synthase gene transcription in human adipocytes. Am J Physiol. 1998, 274: 1253-1259.
Google Scholar
Warnke I, Goralczyk R, Fuhrer E, Schwager J: Dietary constituents reduce lipid accumulation in murine C3H10 T1/2 adipocytes: a novel fluorescent method to quantify fat droplets. Nutr Metab (Lond). 2011, 12 (1): 30-
Article
Google Scholar
Li RW, Theriault AG, Au K, Douglas TD, Casaschi A, Kurowska EM, Mukherjee R: Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters. Life Sci. 2006, 79: 365-373. 10.1016/j.lfs.2006.01.023.
CAS
Article
PubMed
Google Scholar
Lee YS, Cha BY, Saito K, Choi SS, Wang XX, Choi BK, Yonezawa T, Teruya T, Nagai K, Woo JT: Effects of a Citrus depressa Hayata (shiikuwasa) extract on obesity in high-fat diet-induced obese mice. Phytomedicine. 2011, 15: 648-654.
Article
Google Scholar
Farese RV, Sajan MP, Standaert ML: Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes. Exp Biol Med. 2005, 230: 593-605.
CAS
Google Scholar
Kim SW, Muise AM, Lyons PJ, Ro HS: Regulation of adipogenesis by a transcriptional repressor that modulates MAPK Activation. J Biol Chem. 2001, 276: 10199-10206. 10.1074/jbc.M010640200.
CAS
Article
PubMed
Google Scholar
Harmon AW, Patel YM: Naringenin inhibits phosphoinositide 3-kinase activity and glucose uptake in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 2003, 30: 229-234.
Article
Google Scholar
Oreña SJ, Torchia AJ, Garofalo RS: Inhibition of Glycogen-synthase kinase 3 stimulates Glycogen-synthase and Glucose transport by distinct mechanism in 3T3-L1 adipocytes. J Biol Chem. 2000, 275: 15765-15772. 10.1074/jbc.M910002199.
Article
PubMed
Google Scholar
Peng XD, Xu PZ, Chen ML, Hahn-Windgassen A, Skeen J, Jacobs J, Sundararajan D, Chen WS, Crawford SE, Coleman KG, Hay N: Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev. 2003, 17: 1352-1365. 10.1101/gad.1089403.
CAS
Article
PubMed
PubMed Central
Google Scholar