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Neuroendocrine Regulation of Food Intake in Polycystic Ovary Syndrome

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Abstract

Several peripheral and central signals are involved in the sophisticated regulation of food intake. Women with polycystic ovary syndrome (PCOS) are prone to consume a diet higher in saturated fat and foods with high glycemic index and show impaired appetite regulation and measures of satiety. As a consequence, obesity, mostly of the central type, is prevalent in the syndrome and worsens the endocrine and metabolic profile of the affected patients. This review article briefly analyzes the current knowledge about the neuroendocrine mechanisms underlying the interplay between feeding behavior, obesity, and reproductive abnormalities in PCOS.

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Universita Cattolica del Sacro Cuore, Lgo A. Gemelli, 8, 00168, Rome, Italy

    Romualdi Daniela MD PhD, Immediata Valentina MD, De Cicco Simona MD, Tagliafem Valeria MD & Lanzone Antonio MD

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  1. Romualdi Daniela MD PhD
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  2. Immediata Valentina MD
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Correspondence to Immediata Valentina MD.

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Daniela, R., Valentina, I., Simona, D. et al. Neuroendocrine Regulation of Food Intake in Polycystic Ovary Syndrome. Reprod. Sci. 25, 644–653 (2018). https://doi.org/10.1177/1933719117728803

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