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Chemical intermediates scavengers in the therapy of allergic diseases

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Abstract

Although oxidative status has been related to several pathophysiologic processes, there is not a well established connection between antioxidant defense and allergy. An imbalance of reactive oxygen species is related to inflammation in allergic diseases. Antioxidant enzymes are involved in cell detoxification. This primary antioxidant defence system might work against allergic's symptoms. In this work, arguments in favour of the potential of free radical scavengers in antioxidant therapy for allergic patients are discussed.

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Authors and Affiliations

  1. Department of Molecular Biology and Biochemistry, Faculty of Sciences, 29071, Málaga, Spain

    José M. Matés & Cristina Pérez-Gómez

  2. Allergy Service, Hospital Universitario La Paz, 28046, Madrid, Spain

    José M. Segura & Miguel Blanca

  3. Family Medicine Unit of Hospital Carlos Haya, 29010, Málaga, Spain

    Maite Asenjo

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  1. José M. Matés
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  2. José M. Segura
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  3. Cristina Pérez-Gómez
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  4. Maite Asenjo
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  5. Miguel Blanca
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Matés, J.M., Segura, J.M., Pérez-Gómez, C. et al. Chemical intermediates scavengers in the therapy of allergic diseases. Research on Chemical Intermediates 27, 297–304 (2001). https://doi.org/10.1163/156856701300356518

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