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Collapse and hybridization of RNA: View from replica technique approach

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Abstract

The replica technique method is applied to investigate the kinetic behavior of the coarse-grained model for the RNA molecule. A non-equilibrium phase transition of second order between the glassy phase and the ensemble of freely fluctuating structures has been observed. The non-equilibrium steady state is investigated as well and the thermodynamic characteristics of the system have been evaluated. The non-equilibrium behavior of the specific heat is discussed. Based on our analysis, we point out the state in the kinetic pathway in which the RNA molecule is most prone to hybridization.

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Authors and Affiliations

  1. Yerevan State University, 1 A. Manoogian Str., 0025, Yerevan, Armenia

    Y. Sh. Mamasakhlisov & H. Caturyan

  2. INFN-Laboratori Nazionali di Frascati, Via Enrico Fermi, 40, 00044, Frascati RM, Italy

    S. Bellucci

  3. Institute of Physics, Academia Sinica, 128 Sec. 2, Academia Rd., 11529, Nankang, Taipei, Taiwan

    Shura Hayryan & Chin-Kun Hu

  4. Goris State University, 4 Avangard Str., 3204, Goris, Armenia

    Z. Grigoryan

  5. National Center for Theoretical Sciences, National Tsing Hua University, 30013, Hsinchu, Taiwan

    Chin-Kun Hu

  6. Business School, University of Shanghai for Science and Technology, 200093, Shanghai, China

    Chin-Kun Hu

Authors
  1. Y. Sh. Mamasakhlisov
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  2. S. Bellucci
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  3. Shura Hayryan
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  4. H. Caturyan
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  5. Z. Grigoryan
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  6. Chin-Kun Hu
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Correspondence to Chin-Kun Hu.

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Mamasakhlisov, Y.S., Bellucci, S., Hayryan, S. et al. Collapse and hybridization of RNA: View from replica technique approach. Eur. Phys. J. E 38, 100 (2015). https://doi.org/10.1140/epje/i2015-15100-x

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  • DOI: https://doi.org/10.1140/epje/i2015-15100-x

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