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Calculation of survival probabilities for cells exposed to high ion fluences

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Abstract

A methodology of calculations of survival curves with an account for ion tracks interference is developed using the multiscale approach to the physics of radiation damage with ions. The method is applied to cells, for which shouldered survival curves are obtained; however, it can be applied to plasmid DNA and other targets. The recipe is designed for both high and low values of linear energy transfer.

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Author information

Authors and Affiliations

  1. Department of Physics, Oakland University, Rochester, MI, 48309, USA

    Eugene Surdutovich

  2. MBN Research Center, 60438, Frankfurt am Main, Germany

    Andrey V. Solov’yov

  3. On leave from A.F. Ioffe Physical Technical Institute, 194021, St. Petersburg, Russia

    Andrey V. Solov’yov

Authors
  1. Eugene Surdutovich
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  2. Andrey V. Solov’yov
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Corresponding author

Correspondence to Eugene Surdutovich.

Additional information

Contribution to the Topical Issue “Atomic Cluster Collisions”, edited by Alexey Verkhovtsev, Andrey V. Solov’yov, Germán Rojas-Lorenzo, and Jesús Rubayo Soneira.

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Surdutovich, E., Solov’yov, A.V. Calculation of survival probabilities for cells exposed to high ion fluences. Eur. Phys. J. D 72, 140 (2018). https://doi.org/10.1140/epjd/e2018-90022-2

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  • DOI: https://doi.org/10.1140/epjd/e2018-90022-2

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