Abstract
The long-term immunocytogenetically controlled intersubspecific hybridization of domestic pig breeds and wild pigs of European and Asian origin has brought about a new breed population of very small dwarf laboratory pigs that can be used in medicine and biotechnology. The first Russian population of supersmall microsibs is unique in the karyotypic polymorphism in the chromosome set (2n = 36, 37, or 38), as well as unusually short form of the lachrymal bone (os lacrimale) that is not found in any domestic pig breed, very early reproductive prematurity, and specific immunogenic features of the concentrations of the alleles of the EAA, EAD, EAE, EAF, EAG, and EAL blood type loci. Supersmall mini pigs allow one to model a wide range of medical and biotechnologic researches most adequately and economically.
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Original Russian Text © V.N. Tikhonov, V.E. Bobovich, 2011, published in Vavilovskii Zhurnal Genetiki i Selektsii, 2011, Vol. 15, No. 3, pp. 600–609.
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Tikhonov, V.N., Bobovich, V.E. Genetics and major applications of supersmall mini pigs in medicine and biotechnology. Russ J Genet Appl Res 2, 97–104 (2012). https://doi.org/10.1134/S2079059712010145
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DOI: https://doi.org/10.1134/S2079059712010145