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Cystathionine β-synthase in structural elements of the human brain and spinal cord

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Abstract

By means of the immunohistochemical method, the presence and distribution of cystathionine β-synthase (CBS) was studied in nerve cells of the spinal cord and brainstem nuclei in eight men aged 18–44 years who had died as a result of causes not connected with damage to the central nervous system. CBS-positive neurons are revealed in all studied brain parts, in which their content varied in different nuclei from 0.9 to 17%. Large cells of motor nuclei more often had high and very high density of the reaction product deposition. In sensory nuclei the high portion was of small neurons with low intensity of the enzymatic reaction.

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Authors and Affiliations

  1. Vladivostok State Medical University, Vladivostok, Russia

    V. M. Chertok & A. E. Kotsyuba

  2. Zhirmunskii Institute of Marine Biology, Far East Branch, Russian Academy of Sciences, Vladivostok, Russia

    E. P. Kotsyuba

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  1. V. M. Chertok
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  2. A. E. Kotsyuba
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  3. E. P. Kotsyuba
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Correspondence to A. E. Kotsyuba.

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Chertok, V.M., Kotsyuba, A.E. & Kotsyuba, E.P. Cystathionine β-synthase in structural elements of the human brain and spinal cord. Cell Tiss. Biol. 5, 573–579 (2011). https://doi.org/10.1134/S1990519X11060046

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