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Synthesis, Crystal Structure, and Spectral Study of a Novel Indenoimidazole Carboxylic Acid Amide

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Abstract

3a,8a-Dihydroxy-2,8-dioxo-1,3a,8,8a-tetrahydro-2H-indeno[1,2-d]imidazole-3-carboxamide has been synthesized in 85% yield from ninhydrin and biuret via a green facile procedure that is free of workup and column chromatography. The product structure has been established based on FT-IR, NMR, and mass spectra and finally confirmed by single crystal X-ray analysis. The compound crystalized as monoclinic colorless plates with P21/c space group.

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Funding

This work was funded by the Deanship of Scientific Research (DSR), University of Jeddah, Jeddah, under grant No. (UJ-20-077-DR). The authors, therefore, acknowledge with thanks DSR technical and financial support. S.B.N grate­fully acknowledges the support of the Ministry of Education, Science and Technological Development of the Republic of Serbia.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Sciences and Arts – Khulais, University of Jeddah, 21921, Jeddah, Saudi Arabia

    R. M. Ghalib & H. A. H. Alzahrani

  2. Department of Chemistry, S. P. G. College, 226020, Lucknow, India

    S. H. Mehdi

  3. Department of chemistry, Govt. Degree College, 193411, Beerwah, Jammu and Kashmir, India

    A. M. Malla

  4. Department of Chemistry, Faculty of Science, Islamic University of Madinah, 42351, Madinah, Saudi Arabia

    M. G. Alam

  5. Department of Theoretical Physics and Condensed Matter Physics, “VINCA” Institute of Nuclear Sciences – National Institute of the Republic of Serbia, University of Belgrade, 11000, Belgrade, Serbia

    S. B. Novaković

  6. Department of Chemistry, Indian Institute of Technology Kanpur, 208016, Kanpur, Uttar Pradesh, India

    A. K. Gupta

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  1. R. M. Ghalib
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  2. S. H. Mehdi
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  3. A. M. Malla
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  4. M. G. Alam
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  6. A. K. Gupta
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  7. H. A. H. Alzahrani
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Correspondence to R. M. Ghalib.

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Ghalib, R.M., Mehdi, S.H., Malla, A.M. et al. Synthesis, Crystal Structure, and Spectral Study of a Novel Indenoimidazole Carboxylic Acid Amide. Russ J Org Chem 57, 2018–2023 (2021). https://doi.org/10.1134/S1070428021120186

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  • DOI: https://doi.org/10.1134/S1070428021120186

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