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A Novel S-Arylated Dispiro Derivative of 2-Thiohydantoin

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Abstract

A method has been developed for the preparation of a new type of dispiro derivative, 5''-bromo-2-[(4-chlorophenyl)sulfanyl]-1'-methyl-1,4'-diphenyldispiro[imidazole-4,3'-pyrrolidine-2',3''-indoline]-2'',5(1H)-dione, starting from 2-thiohydantoin and using a 1,3-dipolar cycloaddition reaction. The configuration of the target dispiro derivative was unambiguously established by physicochemical methods.

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ACKNOWLEDGMENTS

The authors are grateful to Thermo Fisher Scientific and MS Analitika (Moscow) and personally Prof. A.A. Makarov for the mass spectrometric equipment provided for our use for performing the present work.

Funding

The work was performed by the State Order for the Lomonosov Moscow State University.

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Authors and Affiliations

  1. Lomonosov Moscow State University, 119991, Moscow, Russia

    A. V. Finko, S. P. Stepanova, M. E. Kukushkin, S. V. Kovalev, B. N. Tarasevich, V. A. Chertkov, N. V. Zyk, A. G. Majouga & E. K. Beloglazkina

  2. National University of Science and Technology, 119049, Moscow, Russia

    A. G. Majouga

  3. Mendeleev Russian University of Chemical Technology, 125047, Moscow, Russia

    A. G. Majouga

Authors
  1. A. V. Finko
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  2. S. P. Stepanova
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  3. M. E. Kukushkin
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  4. S. V. Kovalev
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  5. B. N. Tarasevich
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  6. V. A. Chertkov
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  7. N. V. Zyk
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  8. A. G. Majouga
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  9. E. K. Beloglazkina
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Corresponding author

Correspondence to A. V. Finko.

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Finko, A.V., Stepanova, S.P., Kukushkin, M.E. et al. A Novel S-Arylated Dispiro Derivative of 2-Thiohydantoin. Russ J Org Chem 56, 946–948 (2020). https://doi.org/10.1134/S1070428020050322

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  • DOI: https://doi.org/10.1134/S1070428020050322

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