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Synthesis and Spectral, Electrochemical, and Antioxidant Properties of 2-(5-Aryl-6-R-3-phenyl-5,6-dihydro-4H-1,2,4,5-tetrazin-1-yl)-1,3-benzothiazoles

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Abstract

New 2-(5-aryl-6-R-3-phenyl-5,6-dihydro-4H-1,2,4,5-tetrazin-1-yl)-1,3-benzothiazoles were synthesized from the corresponding formazans by alkylation and subsequent cyclization of N-alkyl derivatives. The products were characterized by 1H and 13C NMR, IR, and mass spectra and X-ray diffraction data. Electrochemical properties and antioxidant activity of the synthesized benzothiazole derivatives were studied.

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Acknowledgments

The spectral and analytical data were obtained using the facilities of the Spectroscopy and Analysis of Organic Compounds joint center at the Postovskii Institute of Organic Synthesis (Ural Branch, Russian Academy of Sciences).

Funding

This study was performed in the framework of state assignment (project nos. AAAA-A19-119012290117-6, AAAA-A19-119012490006-1, AAA-A19-119011790130-3) and under financial support by the Ural Branch, Russian Academy of Sciences (project no. 18-3-3-16).

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Authors and Affiliations

  1. Postovsky Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, Yekaterinburg, 620219, Russia

    T. G. Fedorchenko, G. N. Lipunova, A. V. Shchepochkin, M. S. Valova, P. A. Slepukhin & O. N. Chupakhin

  2. Institute of Chemical Technology, Yeltsin Ural Federal University, Yekaterinburg, 620002, Russia

    G. N. Lipunova, A. V. Shchepochkin, A. N. Tsmokalyuk, P. A. Slepukhin & O. N. Chupakhin

Authors
  1. T. G. Fedorchenko
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  2. G. N. Lipunova
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  3. A. V. Shchepochkin
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  4. M. S. Valova
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  5. A. N. Tsmokalyuk
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  6. P. A. Slepukhin
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  7. O. N. Chupakhin
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Corresponding author

Correspondence to T. G. Fedorchenko.

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The authors declare the absence of conflict of interest.

Additional information

Russian Text © The Author(s), 2020, published in Zhurnal Organicheskoi Khimii, 2020, Vol. 56, No. 1, pp. 52–64.

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Fedorchenko, T.G., Lipunova, G.N., Shchepochkin, A.V. et al. Synthesis and Spectral, Electrochemical, and Antioxidant Properties of 2-(5-Aryl-6-R-3-phenyl-5,6-dihydro-4H-1,2,4,5-tetrazin-1-yl)-1,3-benzothiazoles. Russ J Org Chem 56, 38–48 (2020). https://doi.org/10.1134/S1070428020010078

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  • DOI: https://doi.org/10.1134/S1070428020010078

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