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Synthesis of Spiro[benzo[g]chromene-4,3′-pyrroles] by Reaction of Pyrrolediones with Malononitrile and 2-Hydroxynaphthalene-1,4-dione

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Abstract

One-pot reaction of ethyl 1-R-4,5-dioxo-2-phenyl-4,5-dihydro-1H-pyrrole-3-carboxylates with malononitrile and 2-hydroxynaphthalene-1,4-dione in boiling 1,4-dioxane in the presence of triethylamine afforded ethyl 1′-R-2-amino-3-cyano-2′,5,10-trioxo-5′-phenyl-1′,2′,5,10-tetrahydrospiro[benzo[g]chromene- 4,3′-pyrrole]-4′-carboxylates.

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Correspondence to A. N. Maslivets.

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Original Russian Text © T.V. Sal’nikova, M.V. Dmitriev, A.N. Maslivets, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 4, pp. 652–653.

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Sal’nikova, T.V., Dmitriev, M.V. & Maslivets, A.N. Synthesis of Spiro[benzo[g]chromene-4,3′-pyrroles] by Reaction of Pyrrolediones with Malononitrile and 2-Hydroxynaphthalene-1,4-dione. Russ J Org Chem 54, 657–658 (2018). https://doi.org/10.1134/S1070428018040243

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  • DOI: https://doi.org/10.1134/S1070428018040243

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