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Cascade cyclization of methyl 2-(azidomethyl)furan-3-carboxylates with 2-cyanoacetamides. Efficient synthesis of a new heterocyclic system, furo[3,2-e][1,2,3]triazolo- [1,5-a][1,3]diazepine

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Abstract

Cascade cyclization of methyl 2-(azidomethyl)furan-3-carboxylate with 2-cyanoacetamides in the presence of 2 equiv of potassium tert-butoxide afforded a series of N-substituted 5-oxo-5,9-dihydro-4H-furo-[3,2-e][1,2,3]triazolo[1,5-a][1,3]diazepine-3-carboxamides.

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Authors and Affiliations

  1. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, ul. Murmanskaya 5, Kiev, 02660, Ukraine

    M. S. Yagodkina, G. G. Yakovenko, A. V. Bol’but & M. V. Vovk

Authors
  1. M. S. Yagodkina
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  2. G. G. Yakovenko
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  3. A. V. Bol’but
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  4. M. V. Vovk
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Corresponding author

Correspondence to M. V. Vovk.

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Original Russian Text © M.S. Yagodkina, G.G. Yakovenko, A.V. Bol’but, M.V. Vovk, 2017, published in Zhurnal Organicheskoi Khimii, 2017, Vol. 53, No. 4, pp. 626–627.

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Yagodkina, M.S., Yakovenko, G.G., Bol’but, A.V. et al. Cascade cyclization of methyl 2-(azidomethyl)furan-3-carboxylates with 2-cyanoacetamides. Efficient synthesis of a new heterocyclic system, furo[3,2-e][1,2,3]triazolo- [1,5-a][1,3]diazepine. Russ J Org Chem 53, 634–636 (2017). https://doi.org/10.1134/S1070428017040261

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  • DOI: https://doi.org/10.1134/S1070428017040261

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