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Polyfunctional Pyrazoles. 10*. Synthesis of 5-OXO-4,5,7,9-Tetrahydropyrazolo[3,4-е][1,2,3]-Triazolo[1,5-а][1,3]Diazepine-3-Carboxamides in a Tandem Reaction of Ethyl 4-(Azido-Methyl)Pyrazole-3-Carboxylates with Cyanoacetamides

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Chemistry of Heterocyclic Compounds Aims and scope

4-(Azidomethyl)pyrazole-3-carboxylic acid ethyl esters react with cyanoacetamides in THF solution in the presence of t-BuOK resulting in the formation of 5-oxo-4,5,7,9-tetrahydropyrazolo[3,4-e][1,2,3]-triazolo[1,5-a][1,3]diazepine-3-carboxamides.

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Authors and Affiliations

  1. Bukovinian State Medical University, 2 Theatral Sq., Chernivtsy, 58002, Ukraine

    M. K. Bratenko & M. M. Barus

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv, 02094, Ukraine

    M. V. Vovk

Authors
  1. M. K. Bratenko
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  2. M. M. Barus
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  3. M. V. Vovk
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Corresponding author

Correspondence to M. K. Bratenko.

Additional information

*For Communication 9, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1857–1861, December, 2014.

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Bratenko, M.K., Barus, M.M. & Vovk, M.V. Polyfunctional Pyrazoles. 10*. Synthesis of 5-OXO-4,5,7,9-Tetrahydropyrazolo[3,4-е][1,2,3]-Triazolo[1,5-а][1,3]Diazepine-3-Carboxamides in a Tandem Reaction of Ethyl 4-(Azido-Methyl)Pyrazole-3-Carboxylates with Cyanoacetamides. Chem Heterocycl Comp 50, 1707–1711 (2015). https://doi.org/10.1007/s10593-015-1641-5

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  • DOI: https://doi.org/10.1007/s10593-015-1641-5

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