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Synthesis of 6-aryl-N,N-diethyl-4-methyl-2-sulfanylidene-1,2,3,6-tetrahydropyrimidine-5-carboxamides

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Abstract

Three-component condensation of N,N-diethyl-3-oxobutanamide with aromatic aldehydes and thiourea afforded the corresponding 6-aryl-N,N-diethyl-4-methyl-2-sulfanylidene-1,2,3,6-tetrahydropyrimidine-5-carboxamides.

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Authors and Affiliations

  1. Perm State Pharmaceutical Academy, ul. Polevaya 2, Perm, 614990, Russia

    V. L. Gein, N. A. Buzmakova & T. M. Zamaraeva

  2. Perm State National Research University, ul. Bukireva 15, Perm, 614990, Russia

    M. V. Dmitriev

Authors
  1. V. L. Gein
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  2. N. A. Buzmakova
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  3. T. M. Zamaraeva
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  4. M. V. Dmitriev
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Correspondence to V. L. Gein.

Additional information

Original Russian Text © V.L. Gein, N.A. Buzmakova, T.M. Zamaraeva, M.V. Dmitriev, 2016, published in Zhurnal Organicheskoi Khimii, 2016, Vol. 52, No. 4, pp. 581–583.

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Gein, V.L., Buzmakova, N.A., Zamaraeva, T.M. et al. Synthesis of 6-aryl-N,N-diethyl-4-methyl-2-sulfanylidene-1,2,3,6-tetrahydropyrimidine-5-carboxamides. Russ J Org Chem 52, 567–570 (2016). https://doi.org/10.1134/S1070428016040163

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  • DOI: https://doi.org/10.1134/S1070428016040163

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