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Synthesis of 4-(1,4,6-oxadithiocan-5-yl)-1H-pyrazoles

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Abstract

1,3,5-Trialkyl-1H-pyrazole-4-carbaldehydes reacted with 2,2′-oxydiethanethiol in the presence of chloro(trimethyl)silane as dehydrating agent at room temperature to give 4-(1,4,6-oxadithiocan-5-yl)-1H-pyrazole hydrochlorides which were converted into the corresponding free bases by treatment with 5% aqueous ammonia.

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Authors and Affiliations

  1. Favorskii Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, ul. Favorskogo 1, Irkutsk, 664033, Russia

    L. K. Papernaya, A. A. Shatrova & G. G. Levkovskaya

Authors
  1. L. K. Papernaya
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  2. A. A. Shatrova
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  3. G. G. Levkovskaya
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Correspondence to L. K. Papernaya.

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Original Russian Text © L.K. Papernaya, A.A. Shatrova, G.G. Levkovskaya, 2015, published in Zhurnal Organicheskoi Khimii, 2015, Vol. 51, No. 4, pp. 543–546.

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Papernaya, L.K., Shatrova, A.A. & Levkovskaya, G.G. Synthesis of 4-(1,4,6-oxadithiocan-5-yl)-1H-pyrazoles. Russ J Org Chem 51, 526–529 (2015). https://doi.org/10.1134/S1070428015040119

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  • DOI: https://doi.org/10.1134/S1070428015040119

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