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Reaction of 1-aryl-3-(4,4-diethoxybutyl)ureas with phenols. Synthesis of 2-arylpyrrolidines

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Abstract

Acid-catalyzed reaction of phenols with 1-(4,4-diethoxybutyl)urea derivatives gave new 2-arylpyrrolidines containing 4-bromoresorcinol and hydroquinone fragments. The described reaction is advantageous due to its mild conditions and no necessity of using expensive or toxic catalyst.

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Authors and Affiliations

  1. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia

    A. S. Gazizov, A. R. Burilov & M. A. Pudovik

  2. Kazan National Research Technological University, ul. Karla Marksa 68, Kazan, 420015, Tatarstan, Russia

    A. V. Smolobochkin

Authors
  1. A. S. Gazizov
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  2. A. V. Smolobochkin
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  3. A. R. Burilov
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  4. M. A. Pudovik
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Corresponding author

Correspondence to A. S. Gazizov.

Additional information

Original Russian Text © A.S. Gazizov, A.V. Smolobochkin, A.R. Burilov, M.A. Pudovik, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 12, pp. 1828–1831.

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Gazizov, A.S., Smolobochkin, A.V., Burilov, A.R. et al. Reaction of 1-aryl-3-(4,4-diethoxybutyl)ureas with phenols. Synthesis of 2-arylpyrrolidines. Russ J Org Chem 50, 1809–1813 (2014). https://doi.org/10.1134/S1070428014120161

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  • DOI: https://doi.org/10.1134/S1070428014120161

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