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Synthesis and properties of 2-azahetarylaminomethylidene 1,3-dicarbonyl compounds

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Abstract

Reactions of 2-ethoxymethylidene 1,3-dicarbonyl compounds with pyridine-2,6- and pyrimidine-4,5-diamines gave the corresponding 2-hetarylaminomethylidene derivatives. Depending on the initial reactant structure, the formation of mono-and/or bis-condensation products is possible. Hetarylaminomethylidene derivatives showed a moderate tuberculostatic effect. 2-Pyridinylaminomethylidene 3-oxo esters were used as ligands to obtain coordination compounds with d- and f-metal ions.

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Authors and Affiliations

  1. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990, Russia

    Yu. S. Kudyakova, Ya. V. Burgart & V. I. Saloutin

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  1. Yu. S. Kudyakova
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  2. Ya. V. Burgart
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  3. V. I. Saloutin
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Correspondence to Yu. S. Kudyakova.

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Dedicated to Full Member of the Russian Academy of Sciences O.N. Chupakhin on his 80th anniversary

Original Russian Text © Yu.S. Kudyakova, Ya.V. Burgart, V.I. Saloutin, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 6, pp. 863–869.

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Kudyakova, Y.S., Burgart, Y.V. & Saloutin, V.I. Synthesis and properties of 2-azahetarylaminomethylidene 1,3-dicarbonyl compounds. Russ J Org Chem 50, 846–853 (2014). https://doi.org/10.1134/S1070428014060165

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  • DOI: https://doi.org/10.1134/S1070428014060165

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