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Fluoroalkyl-substituted lithium 1,3-diketonates in reactions with hetarylhydrazines

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Abstract

Fluoroalkyl-substituted lithium 1,3-diketonates reacted with 4-hydrazinyl-6-methylpyrimidin-2-amine, 2,6-dimethylpyrimidin-4-ylhydrazine, 7-fluoroquinoxalin-6-ylhydrazine, and benzothiazol-2-ylhydrazine to give the corresponding hetaryl-substituted pyrazoles. The molecular and crystal structures of 4-methyl-6-(3-methyl-5-trifluoromethyl-1H-pyrazol-1-yl)pyrimidin-2-amine and 4-(5-difluoromethyl-4,5,6,7-tetrahydro-2H-indazol-2-yl)-6-methylpyrimidin-2-amine were determined by X-ray analysis.

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Authors and Affiliations

  1. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990, Russia

    N. S. Boltacheva, P. A. Slepukhin, V. I. Filyakova & V. N. Charushin

  2. Institute of Chemical Technology, Ural Federal University, ul. Mira 28, Yekaterinburg, Russia

    L. N. Dianova & V. A. Bakulev

Authors
  1. N. S. Boltacheva
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  2. L. N. Dianova
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  3. P. A. Slepukhin
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  4. V. I. Filyakova
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  5. V. A. Bakulev
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  6. V. N. Charushin
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Corresponding author

Correspondence to V. I. Filyakova.

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Dedicated to Full Member of the Russian Academy of Sciences O.N. Chupakhin on his 80th anniversary

Original Russian Text © N.S. Boltacheva, L.N. Dianova, P.A. Slepukhin, V.I. Filyakova, V.A. Bakulev, V.N. Charushin, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 6, pp. 785–795.

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Boltacheva, N.S., Dianova, L.N., Slepukhin, P.A. et al. Fluoroalkyl-substituted lithium 1,3-diketonates in reactions with hetarylhydrazines. Russ J Org Chem 50, 767–777 (2014). https://doi.org/10.1134/S1070428014060013

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  • DOI: https://doi.org/10.1134/S1070428014060013

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