Abstract
The condensation of 2-amino-1,3-thiazolium perchlorates and their benzo analogs with trifluoroacetylacetone in acetic acid afforded the corresponding [1,3]thiazolo[3,2-a]pyrimidinium, pyrimido[2,1-b][1,3]benzothiazolium, and naphtho[2′,1′:4,5][1,3]thiazolo[3,2-a]pyrimidinium salts as a single isomer in which the trifluoromethyl group is located in the γ-position with respect to the bridgehead nitrogen atom. The structure of the synthesized compounds was confirmed by 1H NMR spectra and elemental analyses.
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Translated from Zhurnal Organicheskoi Khimii, 2021, Vol. 57, No. 3, pp. 384–390 https://doi.org/10.31857/S051474922103006X.
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Shulga, S.I., Simurova, N.V. & Shulga, O.S. Condensation of 2-Amino-1,3-thiazole Salts and Benzo Analogs with Trifluoroacetylacetone. Russ J Org Chem 57, 364–368 (2021). https://doi.org/10.1134/S1070428021030064
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DOI: https://doi.org/10.1134/S1070428021030064