Abstract
Treatment of 1-(2-cyanoethyl)-4-hydroxy-N-(hydroxyalkyl)-2-oxo-1,2-dihydroquinoline-3-carboxamides with a solution of hydrogen chloride in aqueous acetic acid ensures selective transformation of the cyano group into amide or carboxy with simultaneous acetylation of the hydroxyalkyl fragments.
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Original Russian Text © I.V. Ukrainets, O.V. Gorokhova, K.V. Andreeva, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 1, pp. 69–71.
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Ukrainets, I.V., Gorokhova, O.V. & Andreeva, K.V. Synthesis and structure of 3-(3-acetoxyalkylcarbamoyl-4-hydroxy-2-oxo-1,2-dihydroquinolin-1-yl)propanoic acids. Russ J Org Chem 50, 63–65 (2014). https://doi.org/10.1134/S1070428014010126
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DOI: https://doi.org/10.1134/S1070428014010126