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Synthesis of dipeptides based on valine and threonine

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Abstract

Val-Val, Val-Thr, and Thr-Val dipeptides were synthesized using trifluoroacetyl protecting group. The optical rotations of the products were similar to those of samples synthesized using Boc protection, which indicated the absence of racemization in the course of introduction and removal of trifluoroacetyl protection.

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Authors and Affiliations

  1. Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, Minsk, 220072, Belarus

    Yu. M. Sorokina, L. A. Popova & V. A. Knizhnikov

  2. Belarusian State University, Minsk, Belarus

    A. A. Sladkova & O. I. Shadyro

Authors
  1. Yu. M. Sorokina
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  2. A. A. Sladkova
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  3. L. A. Popova
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  4. O. I. Shadyro
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  5. V. A. Knizhnikov
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Corresponding author

Correspondence to V. A. Knizhnikov.

Additional information

Original Russian Text © Yu.M. Sorokina, A.A. Sladkova, L.A. Popova, O.I. Shadyro, V.A. Knizhnikov, 2012, published in Zhurnal Organicheskoi Khimii, 2012, Vol. 48, No. 10, pp. 1302–1306.

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Sorokina, Y.M., Sladkova, A.A., Popova, L.A. et al. Synthesis of dipeptides based on valine and threonine. Russ J Org Chem 48, 1297–1301 (2012). https://doi.org/10.1134/S1070428012100065

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  • DOI: https://doi.org/10.1134/S1070428012100065

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