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Synthesis of new derivatives of 5-alkyl-6-(2,6-dihalobenzyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one and the features of their oxidation

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Abstract

The synthesis and features of the regioselective S-monomethylation of new 5-alkyl-6-(arylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-ones were investigated, and also the character of the oxidative degradation of these compounds when treated with the system H2O2-AcOH.

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Authors and Affiliations

  1. Volgograd State Technical University, Volgograd, 400131, Russia

    I. A. Novakov, B. S. Orlinson, M. B. Navrotskii, A. S. Eremiichuk, L. L. Brunilina, E. A. Gordeeva & E. N. Gerasimov

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  1. I. A. Novakov
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  2. B. S. Orlinson
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  3. M. B. Navrotskii
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  4. A. S. Eremiichuk
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  5. L. L. Brunilina
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  6. E. A. Gordeeva
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  7. E. N. Gerasimov
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Correspondence to I. A. Novakov.

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Original Russian Text © I.A. Novakov, B.S. Orlinson, M.B. Navrotskii, A.S. Eremiichuk, L.L. Brunilina, E.A. Gordeeva, E.N. Gerasimov, 2010, published in Zhurnal Organicheskoi Khimii, 2010, Vol. 46, No. 11, pp. 1684–1687.

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Novakov, I.A., Orlinson, B.S., Navrotskii, M.B. et al. Synthesis of new derivatives of 5-alkyl-6-(2,6-dihalobenzyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one and the features of their oxidation. Russ J Org Chem 46, 1691–1694 (2010). https://doi.org/10.1134/S1070428010110151

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  • DOI: https://doi.org/10.1134/S1070428010110151

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