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α-aminoazoles in the Synthesis of heterocycles: V. Synthesis of azolo[1,5-a]pyrimidines from 2-ethoxyvinyl trifluoromethyl ketones and 2,2-diethoxyvinyl trifluoromethyl ketone

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Abstract

A procedure was proposed for the synthesis of 7-trifluoromethylazolo[1,5-a]pyrimidines by reactions of 2-ethoxyvinyl trifluoromethyl ketones and 2,2-diethoxyvinyl trifluoromethyl ketone with 5(3)-aminoazoles. The reactions occurred under mild conditions, and the products were formed with high yield and regioselectivity.

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Authors and Affiliations

  1. St. Petersburg State University, Universitetskii pr. 26, St. Petersburg, 198504, Russia

    E. E. Emelina & A. A. Petrov

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  1. E. E. Emelina
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  2. A. A. Petrov
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Correspondence to E. E. Emelina.

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Original Russian Text © E.E. Emelina, A.A. Petrov, 2009, published in Zhurnal Organicheskoi Khimii, 2009, Vol. 45, No. 3, pp. 427–430.

For communication IV, see [1].

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Emelina, E.E., Petrov, A.A. α-aminoazoles in the Synthesis of heterocycles: V. Synthesis of azolo[1,5-a]pyrimidines from 2-ethoxyvinyl trifluoromethyl ketones and 2,2-diethoxyvinyl trifluoromethyl ketone. Russ J Org Chem 45, 417–420 (2009). https://doi.org/10.1134/S1070428009030117

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  • DOI: https://doi.org/10.1134/S1070428009030117

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