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Cyclocondensation of N-aryl-3-oxobutanethioamides with 2-aminoimidazole and 2-aminobenzimidazole

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Abstract

Cyclization of N-aryl-3-oxobutanethioamides with 2-aminoimidazole and 2-aminobenzimidazole gave 7-methyl-5,8-dihydroimidazo[1,2-a]pyrimidine-5-thione or 2-methylpyrimido[1,2-a]benzimidazole-4(1H)-thione and 4-(arylamino)-2-methylpyrimido[1,2-a]benzimidazoles whose ratio depends on the nature of aryl substituents in the initial butanethioamides and on the presence of a protic solvent.

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Authors and Affiliations

  1. Kiev National University of Technology and Design, Kiev, Ukraine

    E. I. Maiboroda

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, ul. Murmanskaya 5, Kiev, 02660, Ukraine

    V. N. Britsun

Authors
  1. E. I. Maiboroda
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  2. V. N. Britsun
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Correspondence to V. N. Britsun.

Additional information

Original Russian Text © E.I. Maiboroda, V.N. Britsun, 2008, published in Zhurnal Organicheskoi Khimii, 2008, Vol. 44, No. 8, pp. 1213–1217.

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Maiboroda, E.I., Britsun, V.N. Cyclocondensation of N-aryl-3-oxobutanethioamides with 2-aminoimidazole and 2-aminobenzimidazole. Russ J Org Chem 44, 1200–1204 (2008). https://doi.org/10.1134/S1070428008080162

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  • DOI: https://doi.org/10.1134/S1070428008080162

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