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Reaction of 3-oxo-3-R1-N-R2-propanethioamides with 2-amino-5-R-pyridines

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Abstract

Direction of a reaction between 3-oxo-3-R1-N-R2-propanethioamides and 2-amino-5-R-pyridines in acetic acid depends on the structure of initial thioamides: at R1 = Me, R2 = Ar, Et 2-methyl-7-R-4H-pyrido[1,2-a]-pyrimidine-4-thiones are obtained, and at R1 = Ar, R2 = Me form 1-methyl-5-(N-methylaminothiocarbonyl)-4,6-diaryl-1,2-dihydropyridine-2-thiones.

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Authors and Affiliations

  1. Institute of Organic Chemistry, National Academy of Sciences of the Ukraine, Kiev, 02094, Ukraine

    V. N. Britsun, A. N. Borisevich, V. B. Pirozhenko & M. O. Lozinskii

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  1. V. N. Britsun
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  2. A. N. Borisevich
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  3. V. B. Pirozhenko
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  4. M. O. Lozinskii
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Original Russian Text © V.N. Britsun, A.N. Borisevich, V.B., Pirozhenko, M.O. Lozinskii, 2007, published in Zhurnal Organicheskoi Khimii, 2007, Vol. 43, No. 2, pp. 283–285.

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Britsun, V.N., Borisevich, A.N., Pirozhenko, V.B. et al. Reaction of 3-oxo-3-R1-N-R2-propanethioamides with 2-amino-5-R-pyridines. Russ J Org Chem 43, 276–279 (2007). https://doi.org/10.1134/S1070428007020200

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  • DOI: https://doi.org/10.1134/S1070428007020200

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