Abstract
Biomaterials based on Tokem-200 cation exchanger containing spherical particles were synthesized from solutions using the sol-gel method. The outer frame of the particles is TiO2–SiO2, the inner part is filled with CaO (TiO2–SiO2/CaO sample). The carboxylic cation exchange resin Tokem-200 is characterized by high selectivity with respect to Ca2+ ions, which makes it possible to use it in the development of biomaterials, since calcium is involved in the formation of bone tissue. Conditions for heat treatment of samples were established to produce a homogeneous structure of the material: heat treatment (drying at 60°C), annealing at 150, 250, 350°C for 30 min at each temperature step, annealing at 600°C for 6 h. It was proposed to use gelatin as a binder additive.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
REFERENCES
Przekora, А., Int. J. Mol. Sci., 2019, vol. 20, ID 435. https://doi.org/10.3390/ijms20020435
Aslanidou, M., Vaimakis, T., Mitsionis, A., and Trapalis, C., Ceram. Int., 2013, vol. 39, pp. 539–546. https://doi.org/10.1016/j.ceramint.2012.06.060
Smirnov, V.V., Antonova, O.S., Smirnov, S.V., Goldberg, M.A., Komlev, V.S., and Barinov, S.M., Russ. J. Inorg. Mater., 2017, vol. 53, no. 12, pp. 1254–1260. https://doi.org/10.7868/s0002337x17120065
Ortega, B., Gardner, C., Roberts, S., Chung, A., Wang, J., and Buser, Z, Crit. Rev. Musc. Medic., 2020, vol. 13, no. 4, pp. 530–536. https://doi.org/10.1007/s12178-020-09651-x
Li, H. and Chang, J., Acta Biomater., 2013, vol. 9, pp. 5379–5389. https://doi.org/10.1016/j.actbio.2012.10.019
Borilo, L.P., Kozik, V.V., Lyutova, E.S., Zharkova, V.V., and Brichkov, A.S., Russ. J. Glass Ceram., 2019, vol. 76, nos. 7–8, pp. 315–320. https://doi.org/10.1007/s10717-019-00191-6
Li, X., Wang, M., Deng, Y., Xiao, Y., and Zhang, X., ACS Biomater. Sci. Eng., 2017, vol. 3, no. 8, pp. 1557–1566. https://doi.org/10.1021/acsbiomaterials.7b00232
Balamurugan, A., Sockalingum, G., Michel, J., Fauré, J., Banchet, V., Wortham, L., Bouthors, S., Laurent-Maquin, D., and Balossier, G., Mater. Lett., 2006, no. 60, pp. 3752–3757. https://doi.org/10.1016/j.matlet.2006.03.102
Kokubo, T. and Takadama, H., Biomaterials, 2006, vol. 27, pp. 2907–2915. https://doi.org/10.1016/j.biomaterials.2006.01.017
Vijayalakshmi, U. and Rajeswari, S., Trends Biomater. Artif. Org., 2006, vol. 19, no. 2, pp. 57–62.
Bjоrnоy, S.H., Bassett, D.C., Ucar, S., Andreassen, J.-P., and Sikorski, P.A., Acta Biomater., 2016, no. 44, pp. 254–266. https://doi.org/10.1016/j.actbio.2016.08.041
Borilo, L.P., Lyutova, E.S., and Spivakova, L.N, Key Eng. Mater., 2016, no. 683, pp. 427–432. https://doi.org/10.4028/www.scientific.net/KEM.683.427
Funding
The results were obtained within the framework of the state problem of the Ministry of Education and Science of the Russian Federation, project no. 0721-2020-0037.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
The authors declare that there is no conflict of interest requiring disclosure in this article.
Additional information
Translated from Zhurnal Prikladnoi Khimii, No. 1, pp. 26–31, December, 2022 https://doi.org/10.31857/S0044461822010029
Rights and permissions
About this article
Cite this article
Borilo, L.P., Lyutova, E.S. & Kozik, V.V. Synthesis and Properties of TiO2–SiO2/CaO Biomaterials with Spherical Particles Based on Tokem-200 Cation Exchange Resin. Russ J Appl Chem 95, 21–27 (2022). https://doi.org/10.1134/S1070427222010025
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1070427222010025