Skip to main content
Log in

Formation of Anisotropic Hydroxyapatite Particles under Hydrothermal Conditions

  • Inorganic Synthesis and Industrial Inorganic Chemistry
  • Published:
Russian Journal of Applied Chemistry Aims and scope Submit manuscript

Abstract

Using X-ray diffraction analysis, transmission electron microscopy, and complex thermal analysis, it was shown that brushite crystals are formed from aqueous solutions of ammonium hydrogen phosphate and calcium nitrate. The hydrothermal treatment of brushite results in the formation of quasi-one-dimensional hydroxyapatite nanoparticles, the longitudinal size of which is about 400 nm, and the transverse size is 40 nm. It was demonstrated that hydroxyapatite nanoparticles can be used as fillers of composite matrices for tissue engineering, in particular, in bone grafting.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.

Similar content being viewed by others

REFERENCES

  1. Dobrovolskaya, I.P., Yudin, V.E., Popryadukhin, P.V., and Ivan’kova, E.M., Polymer Scaffolds for Tissue Engineering, St. Petersburg: Mediapapir, 2018.

    Google Scholar 

  2. Paz, A., Guadarrama, D., López, M., González, J.E., Brizuela, N., and Aragón, J., Quimica Nova, 2012, vol. 35, no. 9, pp. 1724–1727. https://doi.org/10.1590/S0100-40422012000900004

    Article  CAS  Google Scholar 

  3. de Caprariis, B., Di Rita, M., Stoller, M., and Verdone, N., Chianese, A., Chem. Eng. Sci., 2012, vol. 76, pp. 73–80. https://doi.org/10.1016/j.ces.2012.03.043

    Article  CAS  Google Scholar 

  4. Landi, E., Logroscino, G., Proietti, L., Tampieri, A., Sandri, M., and Sipro, S., J. Mater. Sci. Mater. Medicine, 2008, vol. 19, no. 1, pp. 239–247. https://doi.org/10.1007/s10856-006-0032-y

    Article  CAS  Google Scholar 

  5. Liu, C., Huang, Y., Shen, W., and Cui, J., Biomaterials, 2001, vol. 22, no. 4, pp. 301–306. https://doi.org/10.1016/S0142-9612(00)00166-6

    Article  CAS  PubMed  Google Scholar 

  6. Dorozhkin, S.V., Mater. Sci. Eng. P., 2015, vol. 55, pp. 272–326. https://doi.org/10.1016/j.msec.2015.05.033

    Article  CAS  Google Scholar 

  7. Karpikhin, A.E., Fedotov, A.Yu., Komlev, V.S., Barinov, S.M., Sirotinkin, V.P., Gordeev, A.S., and Shamrai, V.F., Inorg. Mater., 2016, vol. 52, no. 2, pp. 170–175. https://doi.org/10.1134/S0020168516020060

    Article  CAS  Google Scholar 

  8. Šupová, M., J. Nanosci. Nanotechnol., 2014, vol. 14, no. 1, pp. 546–563. https://doi.org/10.1166/jnn.2014.8895

    Article  CAS  PubMed  Google Scholar 

  9. Dobrovol’skaya, I.P., Tsarev, N.S., Osmolovskaya, O.M., Kasatkin, I.A., Ivan’kova, E.M., Popova, E.N., Pankova, G.A., and Yudin, V.E., Russ. J. Appl. Chem., 2018, vol. 91, no. 3, pp. 368–374. https://doi.org/10.1134/S1070427218030035

    Article  Google Scholar 

  10. Regel’, V.R., Slutsker, A.I., and Tomashevskii, E.E., Soviet Physics Uspekhi, 1972, vol. 15, no. 1, pp. 45–65. https://doi.org/10.1070/PU1972v015n01ABEH004945

    Article  Google Scholar 

  11. Mandel, S. and Tas, A.C., Mater. Sci. Eng. P., 2010, vol. 30, no. 2, pp. 245–254. https://doi.org/10.1016/j.msec.2009.10.009

    Article  CAS  Google Scholar 

Download references

Funding

This work was supported by the Russian Science Foundation, project no. 19-73-30003.

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to T. P. Maslennikova or I. P. Dobrovol’skaya.

Ethics declarations

The authors declare that there is no conflict of interest requiring disclosure in this article.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Maslennikova, T.P., Dobrovol’skaya, I.P., Gatina, E.N. et al. Formation of Anisotropic Hydroxyapatite Particles under Hydrothermal Conditions. Russ J Appl Chem 93, 633–638 (2020). https://doi.org/10.1134/S107042722005002X

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S107042722005002X

Keywords:

Navigation