Abstract
Immobilization of drugs on macromolecules of copolymer N,N-diallyl-N,N-dimethylammonium chloride with sulfur dioxide using ion exchange technique was investigated. Ways of producing polymer-drug conjugates of preset compositions were developed. Their structure was found by NMR and IR spectroscopy.
Similar content being viewed by others
References
Biomedical Polymers, Jenkins, M., Ed., Woodhead Publishing, 2007.
Marychev, S.N. and Kalinin, B.A., Polimery v meditsine (Polymers in Medicine), Vladimir: Vladimir. Gos. Inst., 2001.
Livshits, V.A., Bonartsev, A.P., Iordanskii, A.L. et al., Vysokomol. Soedin., 2009, vol. 51B, no. 7, pp. 1243–1251.
Gushchin, N.A., Ostrovidova, G.U., and Sosnov, E.A., Zh. Prikl. Khim., 2008, vol. 81, no. 1, pp. 132–135.
Panarin, E.F. and Afinogenov, G.E., Zh. Vses. Khim. Obshch. im. D.I. Mendeleeva, 1985, vol. 30, no. 4, pp. 378–386.
Gorbunova, M.N., Vorob’eva, A.I., Aleksandrova, G.A., and Kir’yanova, I.N., Khim.-Farm. Zh., 2009, vol. 43, no. 12, pp. 13–16.
Vorob’eva, A.I., Vasil’eva, E.V., Gaisina, Kh.A., et al., Vysokomol. Soedin., 1996, vol. 38A, no. 10, pp. 1663–1667.
USSR Inventor’s Certificate 1530631.
RF Patent 2095056.
USSR Inventor’s Certificate 1744797.
Harada, S. and Arai, K., Makromol. Chem., 1967, vol. 107, pp. 64–77.
Mudarisova, R.Kh., Kulish, E.I., Zinatullin, R.M. et al., Zh. Prikl. Khim., 2006, vol. 79, no. 10, pp. 1737–1739.
Vorob’eva, A.I., Sagitova, D.R., Kolesov, S.V. et al., Zh. Prikl. Khim., 2008, vol. 81, no. 1, pp. 300–303.
Slerc, P. and Simon, S., Spectral Data for Structure Determination of Organic Compounds, Berlin: Springer-Verlag, 1983.
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © A.I. Vorob’eva, M.S. Babaev, F.A. Sataeva, L.V. Spirikhin, R.R. Muslukhov, S.V. Kolesov, 2012, published in Zhurnal Prikladnoi Khimii, 2012, Vol. 85, No. 11, pp. 1853–1858.
Rights and permissions
About this article
Cite this article
Vorob’eva, A.I., Babaev, M.S., Sataeva, F.A. et al. Copolymer of N,N-diallyl-N,N-dimethylammonium chloride with sulfur dioxide as carrier of drugs. Russ J Appl Chem 85, 1758–1763 (2012). https://doi.org/10.1134/S1070427212110213
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1070427212110213