Abstract
A series of 3-amino-4-substituted phenyl-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-d]pyrimidin-6-imines was synthesized. In vitro antibacterial and antifungal screening indicated that some compounds show good inhibition in comparison with standard drugs amoxycillin, chloramphenicol, ciprofloxacin, norfloxacin, griseofulvin, and nystatin.
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Funding
This work was supported by the Department of Chemistry, Saurashtra University, Rajkot, for providing all the facilities for the completion of this work and the National Facility for Drug Discovery (NFDD), Rajkot for providing spectral data.
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Dubal, G.G., Vachchharajani, P.R., Solanki, M.J. et al. Synthesis, Antibacterial, and Antifungal Screening of New Pyrazolo[3,4-d]pyrimidine Derivatives. Russ J Gen Chem 92, 2734–2739 (2022). https://doi.org/10.1134/S1070363222120234
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DOI: https://doi.org/10.1134/S1070363222120234