Abstract
Synthesis of some new derivatives of N-phenyl-[1,2,4]triazolo [4,3-a]quinoxaline-1-sulfonamide and their in vitro anticancer activity on four human cancer lines like MCF-7 (human breast cancer cell line), HeLa (human cervical cancer cell line), A549 (human lung cancer cell line), and IMR32 (human neuroblastoma cell line) have been studied. Among the products, N-(3,5-dichloronitrophenyl)-[1,2,4] triazolo[4,3-a]quinoxaline-1-sulfonamide, is characterized by the activity higher than the standard Etoposide against the tested cancer cell lines.
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ACKNOWLEDGMENTS
The authors are thankful to the Department of Chemistry, Chaitanya Deemed to be University for providing Laboratory facilities and Department of Biotechnology, Chaitanya Deemed to be University for their support in anticancer activity.
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Pandiri, M., Nukala, S.K., Dasari, G. et al. Design and Synthesis of Some New N-Phenyl-[1,2,4]triazolo[4,3-a]quinoxaline-1-sulfonamide Derivatives and Their Anti-Cancer Activity. Russ J Gen Chem 91, 2280–2285 (2021). https://doi.org/10.1134/S1070363221110153
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DOI: https://doi.org/10.1134/S1070363221110153