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Synthesis of New Fused Furo- and Thienopyridines

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Abstract

A method was developed for the synthesis of new fused derivatives of pyrano[4,3-b]thieno(furo)-pyridine, namely 8,8-dimethyl-11-(2-furyl)-7,10-dihydro-8H-pyrano[3″,4″:5′,6′]pyrido[3′,2′:4,5]thieno(furo)[3,2-d]- pyrimidine-4(3H)-ones, from 2,2-dimethyltetrahydropyran-4-one. Optimal conditions for carrying out the cyclization reaction of ethyl {7,7-dimethyl-4-(2-furyl-3-cyano-7,8-dihydro-5H-pyrano[4,3-b]pyridin-2-yl]oxy}acetate into the corresponding amino ester were determined.

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Authors and Affiliations

  1. Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia, Yerevan, 0014, Armenia

    V. V. Dabaeva, M. R. Baghdasaryan, E. G. Paronikyan, R. A. Tamazyan, A. G. Ayvazyan & Sh. Sh. Dashyan

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  1. V. V. Dabaeva
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  2. M. R. Baghdasaryan
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  3. E. G. Paronikyan
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  4. R. A. Tamazyan
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  5. A. G. Ayvazyan
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  6. Sh. Sh. Dashyan
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Corresponding author

Correspondence to V. V. Dabaeva.

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Russian Text © The Author(s), 2019, published in Zhurnal Obshchei Khimii, 2019, Vol. 89, No. 12, pp. 1842–1847.

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Dabaeva, V.V., Baghdasaryan, M.R., Paronikyan, E.G. et al. Synthesis of New Fused Furo- and Thienopyridines. Russ J Gen Chem 89, 2364–2368 (2019). https://doi.org/10.1134/S1070363219120065

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  • DOI: https://doi.org/10.1134/S1070363219120065

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