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An Efficient Microwave Assisted Synthesis and Antimicrobial Activty of 1,2,3-Triazolyl-pyrrolidinyl-quinolinolines

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Abstract

A novel series of 1,2,3-triazolyl-pyrrolidinyl-quinolinolines are synthesised by the Click reaction of alkynes with aromatic azides catalysed by CuI under microwave assisted and conventional conditions. All synthesized 1,2,3-triazoles are screened for their in vitro antimicrobial activity against different bacterial and fungal pathogens. Majority of the synthesized compounds demonstrate moderate to good inhibition zones compared to the standard drugs.

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Authors and Affiliations

  1. Department of Chemistry, Osmania University, Hyderabad, Telangana, 500007, India

    M. Pradeep, M. Vishnuvardhan, V. Bala Krishna & R. Madhusudhan Raju

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  1. M. Pradeep
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  2. M. Vishnuvardhan
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  3. V. Bala Krishna
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  4. R. Madhusudhan Raju
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Correspondence to R. Madhusudhan Raju.

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Pradeep, M., Vishnuvardhan, M., Bala Krishna, V. et al. An Efficient Microwave Assisted Synthesis and Antimicrobial Activty of 1,2,3-Triazolyl-pyrrolidinyl-quinolinolines. Russ J Gen Chem 89, 313–318 (2019). https://doi.org/10.1134/S1070363219020233

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  • DOI: https://doi.org/10.1134/S1070363219020233

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