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Synthesis and Properties of [4-(Diethylamino)phenyl]dichlorophosphine

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Abstract

[4-(Diethylamino)phenyl]dichlorophosphine synthesized for the first time has reacted with trialkyl orthoformate and ethylene oxide in the presence of ethyl chloroacetate with the formation of phosphorylated formals and ethyl [4-(diethylamino)phenyl](2-chloroethoxy)phosphonyl acetate, a precursor of a new analog of nootropic drug KAPAKh.

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Correspondence to M. B. Gazizov.

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Russian Text © M.B. Gazizov, Sh.N. Ibragimov, O.D. Khairullina, S.Yu. Ivanova, K.S. Gazizova, R.A. Khairullin, Yu.S. Kirillina, A.L. Pistsova, 2019, published in Zhurnal Obshchei Khimii, 2019, Vol. 89, No. 1, pp. 73–77.

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Gazizov, M.B., Ibragimov, S.N., Khairullina, O.D. et al. Synthesis and Properties of [4-(Diethylamino)phenyl]dichlorophosphine. Russ J Gen Chem 89, 63–66 (2019). https://doi.org/10.1134/S1070363219010110

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  • DOI: https://doi.org/10.1134/S1070363219010110

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