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Synthesis of 2-thioxo-4,6-diphenyl-1,2-dihydronicotinonitrile via condensation of benzaldehyde with cyanothioacetamide and p-(1-styryl)morpholine

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Abstract

2-Thioxo-4,6-diphenyl-1,2-dihydronicotinonitrile has been prepared via condensation of benzaldehyde with cyanothioacetamide and N-(1-styryl)morpholine; alkylation of the product with alkyl halides has afforded substituted 2-alkylsulfanyl-4,6-diphenylnicotinonitriles and 3-amino-2-acyl-4,6-diphenylthieno[2,3-b]pyridines.

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Authors and Affiliations

  1. Shevchenko Lugansk University, ul. Oboronnaya 2, Lugansk, 91011, Ukraine

    I. V. Dyachenko & V. D. Dyachenko

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  1. I. V. Dyachenko
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  2. V. D. Dyachenko
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Correspondence to I. V. Dyachenko.

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Original Russian Text © I.V. Dyachenko, V.D. Dyachenko, 2015, published in Zhurnal Obshchei Khimii, 2015, Vol. 85, No. 6, pp. 980–984.

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Dyachenko, I.V., Dyachenko, V.D. Synthesis of 2-thioxo-4,6-diphenyl-1,2-dihydronicotinonitrile via condensation of benzaldehyde with cyanothioacetamide and p-(1-styryl)morpholine. Russ J Gen Chem 85, 1447–1451 (2015). https://doi.org/10.1134/S1070363215060146

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  • DOI: https://doi.org/10.1134/S1070363215060146

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