Skip to main content
SpringerLink
Log in

Thermal stability of amino acids

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

Thermal decomposition of L-α-amino acids RCH2(NH2)COOH where R = Me2CH, Me2CHCH2, MeEtCH, and C6H5CH2 was studied at temperatures below the melting points of their crystals. From the effective rate constants of the first order reactions energy parameters in the Arrhenius equation were calculated. Correlations between the reaction rate constants k R and the inductive constants σ* of substituents R and also between the rate constants of the reactions and the dipole moments of amino acids was established. Value of ρ* parameter +8.8 in the Taft equation indicates the heterolytic mechanism of transformation of the amino acids. Chromato-mass spectrometric analysis of decomposition products shows that condensation, decarboxylation, and deamination of the amino acids take place.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Coppens, P.H., Abramov, Yu., Carducci, M., Korjov, B., Novozhilva, I., and Alhambra, C., J. Am. Chem. Soc., 1999, vol. 121, p. 2585.

    Article  CAS  Google Scholar 

  2. Kondrat’ev, M.S., Samchenko, A.A., Komarov, V.M., and Kabanov, F.V., Trudy Mezhdunar. konf. MKO (Proc. of MKO Int. Conf.), Pushchino, 2005, vol. 3, p. 899.

    Google Scholar 

  3. Vatagin, V.S. and Badelin, V.G., Zh. Khim. Termodin. i Termokhim., 1993, vol. 2,no. 1, p. 101.

    CAS  Google Scholar 

  4. Yablokov, V.A., Smel’tsova, I.L., Zelyaev, I.A., and Mitrofanova, S.V., Zh. Obshch. Khim., 2009, vol. 79,no. 8, p. 1344.

    Google Scholar 

  5. Yablokov, V.A., Vasina, Ya.A., Zelyaev, I.A., and Mitrofanova, S.V., Zh. Obshch. Khim., 2009, vol. 79,no. 6, p. 969.

    Google Scholar 

  6. Zhdanov, Yu.A. and Minkin, V.I, Korrelyatsionnyi analiz v organicheskoi khimii (Correlation Analysis in Organic Chemistry), Rostovskii Univ., 1966.

    Google Scholar 

  7. Tyukavkina, N.A., Baukov, Yu.I., Bioorganicheskaya khimiya (Bioorganic Chemistry), Moscow: Drofa, 2010.

    Google Scholar 

  8. Badelin, V.G., Tyunina, E.Yu., Girichev, G.V., Giricheva, N.I., and Pelipets, O.V., Zh. Strukt. Khim., 2007, vol. 48,no. 4, p. 698.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Nizhny Novgorod State Architectural and Constructing University, ul. Il’inskaya 65, Nizhny Novgorod, 603600, Russia

    V. A. Yablokov & I. L. Smel’tsova

  2. Scientific and Research Institute of Chemistry at Lobachevskii Nizhny Novgorod State University, Nizhny Novgorod, Russia

    V. I. Faerman

Authors
  1. V. A. Yablokov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. L. Smel’tsova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. I. Faerman
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to I. L. Smel’tsova.

Additional information

Original Russian Text © V.A. Yablokov, I.L. Smel’tsova, V.I. Faerman, 2013, published in Zhurnal Obshchei Khimii, 2013, Vol. 83, No. 3, pp. 423–427.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yablokov, V.A., Smel’tsova, I.L. & Faerman, V.I. Thermal stability of amino acids. Russ J Gen Chem 83, 476–480 (2013). https://doi.org/10.1134/S1070363213030122

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363213030122

Keywords

Search

Navigation