Abstract
The heterocyclization of 2-thiocyanato-3-arylpropionamides in acetic anhydride followed by the deacylation of the intermediates formed in an alkaline medium afforded the otherwise difficultly accessible 2-amino-5-benzylthiazol-4-ones.
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Original Russian Text © B.D. Grishchuk, V.S. Baranovskii, 2011, published in Zhurnal Obshchei Khimii, 2011, Vol. 81, No. 9, pp. 1559–1562.
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Grishchuk, B.D., Baranovskii, V.S. Synthesis of 5-arylsubstituted thiazol-4-one acetyl and amino derivatives by the heterocyclization of the products of acrylamide thiocyanatoarylation. Russ J Gen Chem 81, 1896 (2011). https://doi.org/10.1134/S1070363211090271
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DOI: https://doi.org/10.1134/S1070363211090271