Skip to main content
SpringerLink
Log in

Synthesis and mechanism of formation of 5-benzylidene-2-thioxo-2,3-dihydro-(1H,5H)-pyrimidine-4,6-diones difluoromethoxy derivatives

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

Reactions of 5-benzylidene-2-thioxo-2,3-dihydro-(1H,5H)-pyrimidine-4,6-diones with a singlet difluorocarbene afford difluoromethoxy derivatives in 20–34% yield. The quantum-chemical analysis of the reaction mechanism showed that N,N-dimethylformamide is involved into the formation of difluoromethoxy derivatives.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Yagupol’skii, L.M., Fialkov, Yu.A., and Tarasova, E.V., Khim.-Farm. Zh., 2006, vol. 40, no. 4, p. 15.

    Google Scholar 

  2. Levina, R.Ya., Usp. Khim., 1960, vol. 29, no. 8, p. 929.

    CAS  Google Scholar 

  3. Rakhimov, A.I. and Avdeev, S.A., Zh. Obshch. Khim., 2009, vol. 79, no. 11, p. 1890.

    Google Scholar 

  4. Schmidt, M.W.S., J. Comput. Chem., 1993, no. 14, p. 1347.

  5. Petko, K.I. and Yagupol’skii, L.M., Zh. Obshch. Khim., 2004, vol. 40, no. 40, p. 627.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Volgograd State Technical University, pr. Lenina 28, Volgograd, 400131, Russia

    A. I. Rakhimov & I. Yu. Kameneva

  2. Institute of Chemical Problems in Ecology, Russian Academy of Natural Sciences, Volgograd, Russia

    S. A. Avdeev & R. G. Fedunov

Authors
  1. A. I. Rakhimov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. Yu. Kameneva
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. A. Avdeev
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. G. Fedunov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. I. Rakhimov.

Additional information

Original Russian Text © A.I. Rakhimov, I.Yu. Kameneva, S.A. Avdeev, R.G. Fedunov, 2011, published in Zhurnal Obshchei Khimii, 2011, Vol. 81, No. 2, pp. 317–321.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rakhimov, A.I., Kameneva, I.Y., Avdeev, S.A. et al. Synthesis and mechanism of formation of 5-benzylidene-2-thioxo-2,3-dihydro-(1H,5H)-pyrimidine-4,6-diones difluoromethoxy derivatives. Russ J Gen Chem 81, 415–419 (2011). https://doi.org/10.1134/S1070363211020228

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363211020228

Keywords

Search

Navigation