Abstract
The synthesis and data on the physicochemical characteristics and biological activity of the new iron nitrosyl complex (Q+)2[Fe2(S2O3)2(NO)4]2– (I), where Q+ is protonated 2-ethyl-4-pyridinecarbothioamide (C8H11N2S), are presented. The structure and properties of the complex were studied by X-ray diffraction, elemental analysis, IR and Mössbauer spectroscopy, and amperometry. The complex showed antibacterial activity and efficiently inhibited cyclic guanosine monophosphate phosphodiesterase (cGMP PDE), which may suggest its antihypertensive, anti-aggregation, and vasodilator activities.
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This study was supported by the Ministry of Science and Higher Education of the Russian Federation (State Assignment no. AAAA-A19-119071890015-6).
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Sanina, N.A., Shilov, G.V., Ovanesyan, N.S. et al. Synthesis, Structure, and Properties of the Iron Nitrosyl Complex with 2-Ethyl-4-pyridinecarbothioamide. Russ J Coord Chem 49, 542–554 (2023). https://doi.org/10.1134/S1070328423600523
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DOI: https://doi.org/10.1134/S1070328423600523