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Isolation of actinium-225 for medical purposes

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Abstract

A procedure is described for isolation and purification of 225Ac as a 229Th daughter decay product using ion exchange. The process includes the following steps: separation of 229Th from a mixture of 225Ac and 225Ra (225Ac precursor) using an anion-exchange resin; separation of 225Ac and 225Ra using a cation-exchange resin; purification of 225Ac to remove inactive impurity cations (primarily Fe) using an anion-exchange resin; final purification of the product on a column with a cation-exchange resin.

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Authors and Affiliations

  1. Leipunskii Institute for Physics and Power Engineering, pl. Bondarenko 1, Obninsk, Kaluga oblast, Russia

    A. A. Kotovskii, N. A. Nerozin, I. V. Prokof’ev, V. V. Shapovalov, Yu. A. Yakovshchits, A. S. Bolonkin & A. V. Dunin

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  1. A. A. Kotovskii
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  2. N. A. Nerozin
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  3. I. V. Prokof’ev
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  4. V. V. Shapovalov
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  5. Yu. A. Yakovshchits
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  6. A. S. Bolonkin
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  7. A. V. Dunin
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Corresponding author

Correspondence to V. V. Shapovalov.

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Original Russian Text © A.A. Kotovskii, N.A. Nerozin, I.V. Prokof’ev, V.V. Shapovalov, Yu.A. Yakovshchits, A.S. Bolonkin, A.V. Dunin, 2015, published in Radiokhimiya, 2015, Vol. 57, No. 3, pp. 241–246.

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Kotovskii, A.A., Nerozin, N.A., Prokof’ev, I.V. et al. Isolation of actinium-225 for medical purposes. Radiochemistry 57, 285–291 (2015). https://doi.org/10.1134/S1066362215030091

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  • DOI: https://doi.org/10.1134/S1066362215030091

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