Abstract
2-Methyl-5-(p-methoxyphenyl)benzoic acid N-methylamide and N-methyl-N-(2-methyl-4-methoxy-5-trifluoromethylphenyl)-N′-methylurea, labeled with hydrogen isotopes, were prepared. The number of the incorporated deuterium atoms per molecule was 5.4 for 2-methyl-5-(p-methoxyphenyl)benzoic acid N-methylamide and 1.82 for N-(2-methyl-4-methoxy-5-trifluoromethylphenyl)-N′-methylurea. The molar radioactivities of the tritium-labeled forms of these compounds reached 90 and 30 Ci mmol−1, respectively.
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Shevchenko, V.P., Nagaev, I.Yu, Shevchenko, K.V., and Myasoedov, N.F., Radiochemistry, 2013, vol. 55, no. 3, pp. 346–351.
Shevchenko, V.P., Nagaev, I.Yu., and Myasoedov, N.F., Mechennye tritiem lipofil’nye soedineniya (Tritium-Labeled Lipophilic Compounds), Moscow: Nauka, 2003.
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Original Russian Text © V.P. Shevchenko, I.Yu. Nagaev, N.F. Myasoedov, 2014, published in Radiokhimiya, 2014, Vol. 56, No. 3, pp. 249–251.
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Shevchenko, V.P., Nagaev, I.Y. & Myasoedov, N.F. Introduction of deuterium and tritium into 2-methyl-5-(p-methoxyphenyl)benzoic acid N-methylamide and N-methyl-N-(2-methyl-4-methoxy-5-trifluoromethylphenyl)-N′-methylurea. Radiochemistry 56, 292–295 (2014). https://doi.org/10.1134/S1066362214030114
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DOI: https://doi.org/10.1134/S1066362214030114